肺癌围手术期患者血清皮质醇与C型行为特征的相关性研究

The correlation study between the serum cortisol and C type behaviors of perioperative patients with lung cancer

目的 探讨肺癌围手术期患者血清皮质醇与C型行为特征的相关性.方法 以安徽省立医院胸外科术前100例肺癌患者作为研究对象,采用一般资料问卷、血清皮质醇检测、C型行为量表对他们的一般资料、血清皮质醇水平及C型行为特征进行调查.结果 肺癌围手术期患者血清皮质醇水平为（447.85±87.65） μg/L.男性患者C型行为焦虑维度得分高于正常人,P＜0.05;抑郁维度得分高于正常人,P＜0.01;愤怒外向、理智、乐观、社会支持维度得分低于正常人,P＜0.01.肺癌围手术期患者血清皮质醇与患者C型行为的焦虑、抑郁、愤怒内向得分呈正相关,r=0.215、0.241、0.225,P＜0.05;肺癌围手术期患者血清皮质醇与患者C型行为的乐观、社会支持得分呈负相关,r=-0.223、-0.276,P＜0.05.结论 肺癌围手术期患者血清皮质醇水平较高,且与患者C型行为特征之间存在相关性.

Objective To discuss the correlation between the serum cortisol level and C type behaviors of perioperative patients with lung cancer.Methods A total of 100 patients from the thoracic department of Anhui Provincial Hospital were enrolled as the study object.The general information,the serum cortisol level,the C type behavior of perioperative patients with lung cancer were investigated by using the General Information Questionnaire,Serum cortisol testing and C Type Behavior Scales.Results The serum cortisol level of 100 patients was （447.85±87.65） μg/L.The C Type Behaviors Scale showed that the scores of anxiety were significantly higher in these patients than in the norm,P＜0.05,depression scores were significantly higher in these patients than in the norm,P＜0.01,while the extroversion anger,reason,optimism and social support were significantly lower,P＜0.01.The serum cortisol of patients was positively correlated with anxiety,depression and introversion anger of C type behaviors,r=0.215,0.241,0.225,P＜ 0.05.The serum cortisol of patients was negatively correlated with optimism and social support of C type behaviors,r=-0.223,-0.276,P＜0.05.Conclusions The serum cortisol level of perioperative patients was higher than the norm,and correlated with the C type behaviors.