期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Nogo-A and its functions beyond axonal inhibition: the controversial role of Nogo-A in Parkinson's disease

Nogo-A and its functions beyond axonal inhibition: the controversial role of Nogo-A in Parkinson's disease
下载PDF
导出
摘要 Nogo-A belongs to the reticulon family（RTN4）and is generally assumed to be one of the most potent myelin associated neurite outgrowth inhibitors in the central nervous system（CNS）.Together with other inhibitors such as the myelin associated glycoprotein（MAG）,oligodendrocyte myelin glycoprotein（OMgp）, Nogo-A belongs to the reticulon family（RTN4）and is generally assumed to be one of the most potent myelin associated neurite outgrowth inhibitors in the central nervous system（CNS）.Together with other inhibitors such as the myelin associated glycoprotein（MAG）,oligodendrocyte myelin glycoprotein（OMgp）,
作者 Stefanie Seiler Hans R.Widmer
机构地区 Department of Neurosurgery Graduate School for Cellular and Biomedical Sciences
出处 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第8期1223-1224,共2页 中国神经再生研究（英文版）
基金 supported by the HANELA Foundation and the Swiss National Science Foundation(No.31003A_135565)
关键词 Nogo axonal myelin belongs glycoprotein potent controversial assumed Together amyotrophic Nogo axonal myelin belongs glycoprotein potent controversial assumed Together amyotrophic
分类号 R742.5 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献11

  • 1Inoue H, Lin L, Lee X, Shao Z, Mendes S, Snodgrass-Belt P, Sweigard H, Engber T, Pepinsky B, Yang L, Beal MF, Mi S, Isacson O (2007) Inhibition of the leucine-rich repeat protein I.INGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson’s disease models. Proc Natl Acad Sci USA 104:14430-14435.
  • 2Kurowska Z, Brundin P, Schwab ME, Li JY (2014) Intracellular Nogo-A facilitates initiation of neurite formation in mouse midbrain neurons in vitro. Neuroscience 256:456-466.
  • 3Mi S, Pepinsky RB, Cadavid I) (2013) Blocking LINGO-1 as a therapy to promote CNS repair: from concept to the clinic. CNS Drugs 27:493-503.
  • 4Saha N, Kolev M, Nikolov DB (2014) Structural features of the Nogo receptor signaling complexes at the neuron/myelin interface. Neurosci Res 87:1-7.
  • 5Schawkat K, Di Santo S, Seiler S, Ducray AD, Widmer HR (2015) Loss of Nogo-A-expressing neurons in a rat model of Parkinson’s disease. Neuroscience 288:59-72.
  • 6Schmandke A, Schmandke A, Schwab ME (2014) Nogo-A: Multiple Roles in CNS development, maintenance, and disease. Neuroscientist 20:372-386.
  • 7Schwab ME, Caroni P (1988) Oligodendrocytes and CNS myelin are non-permissive substrates for neurite growth and fibroblast spreading in vitro.I Neurosci 8:2381-2393.
  • 8Schwab ME, Strittmatter SM (2014) Nogo limits neural plasticity and recovery from injury. Curr Opin Neurobiol 27:53-60.
  • 9Seiler S, Pollini D, Di Santo S, Widmer HR (2013) Antagonizing Nogo-re-ceptor 1 promotes the number of cultured dopaminergic neurons and elongates their neurites. Neuroreport 24:1047-1052.
  • 10Teng FY, Tang BL (2005) Why do Nogo/Nogo-66 receptor gene knockouts result in inferior regeneration compared to treatment with neutralizing agents? J Neurochem 94:865-874.
Neural Regeneration Research
2015年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部