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血甘油三酯对非酒精性脂肪性肝病患者PAI-1及APN水平的影响

Effect of Serum Triglyceride on PAI-1 and APN Levels in Patients with Nonalcoholic Fatty Liver Disease
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摘要 目的研究血甘油三酯对非酒精性脂肪性肝病(NAFLD)患者PAI-1及APN水平的影响。方法选取2012年1月~2014年6月来我院进行诊治符合NAFLD诊断标准,经超声检查确诊为NAFLD患者38例,按血甘油三酯水平分为观察A组和观察B组,并选取同期到我院进行体检的健康人群22例作为正常对照组,比较三组患者的一般情况以及血糖、尿酸、PAI-1、APN水平。结果与正常对照组相比:观察A组患者TG、PAI-1、APN水平无显著性变化,差异无统计学意义(P〉0.05);观察B组患者TG、PAI-1水平显著升高,APN水平显著降低,差异具有统计学意义(P〈0.05);观察B组患者TG、PAI-1、APN水平与观察A组相比无显著性变化(P〉0.05)。结论 NAFLD患者PAI-1和APN水平受血甘油三酯的影响,具体表现为PAI-1升高和APN降低,临床诊治中观察NAFLD患者PAI-1和APN水平的变化,可以为防治NAFLD相关的心血管疾病提供参考。
出处 《现代诊断与治疗》 CAS 2015年第15期3375-3377,共3页 Modern Diagnosis and Treatment
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