代谢综合征对40-50岁男性人群前列腺体积的影响

Effects of metabolic syndrome on prostate volume in men aged from 40 to 50 years

目的研究代谢综合征（metabolic syndrome,MS）对40-50岁男性人群前列腺体积的影响。方法回顾2010年1月-2013年12月本院体检中心438例40-50岁男性体检资料,评价前列腺体积与代谢综合征的相关性。结果 MS组（89例）前列腺体积（18.66±6.26）cc,非MS组（349例）前列腺体积（17.11±3.41）cc（P〈0.05）。空腹血糖异常[（18.99±5.58）cc]及腰围异常[（19.22±5.54）cc]者较非MS组前列腺体积显著增大（P〈0.05）。Logistic回归分析显示,40-50岁男性人群空腹血糖异常及腰围异常与前列腺体积显著相关（P〈0.05）。结论 40-50岁男性人群空腹血糖异常及腰围异常与前列腺体积显著相关。

Objective To evaluate effects of metabolic syndrome（MS） and MS-related parameters on prostate volume in men aged from 40 to 50 years. Methods A total of 438 men aged from 40 to 50 years admitted to our hospital from January 2010 to December 2013 were enrolled in this study. The correlations of prostate volume with MS and MS-related parameters were evaluated.Results Prostate volume was not significantly larger in MS group [（18.66±6.26） cc] than in non-MS group [（17.11±3.41） cc, P〈0.05]. Compared with non-MS group, the prostate volume in subjects with abnormal fasting plasma glucose [FPG,（18.99±5.58）cc]and abnormal waist circumference [WC,（19.22±5.54） cc] were significantly larger（P〈0.05）. The logistic regression analysis showed that FPG level and WC had significantly positive correlation with prostate volume（P〈0.05）. Conclusion Groups with abnormal FPG and WC have larger prostate volume than normal groups, which are the important factors in prostate volume enlargement in men aged from 40 to 50 years.