不同病原体所致的社区获得性肺炎与幽门螺旋杆菌关系

Correlation between helicobacter pylori and community-acquired pneumonia caused by different pathogens

目的探讨幽门螺旋杆菌(HP)在不同病原体(肺炎链球菌、流感嗜血性杆菌、支原体、衣原体)所致社区获得性肺炎中的感染率是否有差异。并了解不同病原体之间是否存在HP感染率差异。方法采用Elisa方法检测血清中HP抗体。并与正常对照组的血清进行对比分析。结果四种病原体所致的肺炎患者其血清中的HP抗体与正常人群血清HP抗体比较,HP感染率均较正常对照组增高,以肺炎链球菌与流感嗜血杆菌(革兰氏阳性菌组)增高更为明显,P<0.05。结论 HP血清抗体阳性率在社区获得性肺炎中升高,HP感染可能增加社区获得性肺炎感染的几率。

Objective To explore the correlation between helicobacter pylori and community-acquired pneu- monia caused by different pathogens pneumonia, including streptococcus pneumoniae, haemophilus influenza bacil- lus, mycoplasma and chlamydia. Methods HP antibody in serum were detected by Elisa method, which was com- paratively analyzed with the normal control group. Results Compared with the normal control group, the positive rate of serum HP antibody in community-acquired pneumonia patients increased significantly, and the increase was more pronounced in the streptococcus pneumoniae and Haemophilus influenzae group （ P 〈 0. 05）. Conclusion The positive rate of serum HP antibody in community-acquired pneumonia patients increases, and HP infection may result in community-acquired pneumonia.