肺泡灌洗治疗慢性阻塞性肺疾病急性加重期并呼吸衰竭

Bronchoscopy combined with lavage in the treatment of AECOPD patients complicated with respiratory failure

目的探讨纤维支气管镜联合肺泡灌洗治疗慢阻肺急性加重期合并呼吸衰竭的价值。方法选取我院收治的慢阻肺急性加重期合并呼吸衰竭患者60例随机分组,对照组行普通吸痰管吸痰,纤支镜组行纤支气管吸痰联合肺泡灌洗。结果纤支镜组治疗后Pa O2、Sa O2水平显著高于对照组,Pa CO2、CRP和PCR水平显著低于对照组P<0.01。纤支镜组呼吸衰竭纠正时间、有创通气时间、感染控制窗出现及住院时间均显著短于对照组P<0.01。结论纤支镜联合肺泡灌洗治疗慢阻肺急性加重期合并呼吸衰竭,应用价值较高,吸痰效果好,有效促进患者气道通畅和改善炎症反应。

Objective To investigate the value of bronchoscope combined with lavage in the treatment of AECOPD patients complicated with respiratory failure. Methods 60 AECOPD patients complicated with respiratory failure were randomly divided into two groups. The control group was given ordinary routine suction tube suctioning, and the bronchoseopy group was given bronchial suctioning fiber joint lavage. Results After the treatment, the lev- els of PaO2 and SaO2 were significantly higher in the bronchoseopy group than in the control group, and the levels of PaCO2 , CRP and PCR were significantly lower in the bronehoseopy group than in the control group （P 〈 0. 01 ）. Re- spiratory failure correct time, invasive ventilation time, infection control window appearing time and duration of hospi- tal stay were significantly shorter in the bronchoscopy group than in the control group （ P 〈 0. 01 ）. Conclusion Bronchoscope expectoration combined with lavage has high application value in the treatment of AECOPD patients complicated with respiratory failure, which can effectively promote sputum suction improve airway inflammation.