低剂量螺旋 CT 扫描在肺癌早期诊断中的临床应用被引量：5

Clinical application of low-dose CT scanning in early diagnosis of lung cancer

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摘要目的：研究低剂量螺旋 CT 扫描在肺癌早期诊断中的临床应用。方法对常规剂量CT（100 mA —200 mA）肺部检查发现肺部肿块的60例患者，应用低剂量CT（40 mA 、30 mA 、20 mA）进一步筛查评估，分别统计肺癌诊断准确率。结果常规剂量CT对肺癌诊断准确率为78．7％，低剂量 CT40 mA 、30mA、20mA组对肺癌诊断准确率分别为75．6％、70．3％、55．6％；低剂量CT40mA 组、低剂量 CT30 mA 组与常规剂量 CT 组肺癌诊断准确率比较差异无显著性（χ^2＝0．12、0．79，P＞0．05），低剂量 CT20 mA 组与常规剂量CT组肺癌诊断准确率比较差异有显著性（χ^2＝5．09，P＜0．05）结论低剂量螺旋CT 30 mA）扫描有较高的敏感性，较低的辐射量，可用于肺癌早期筛查。 Objective To survey clinical application of low‐dose CT scanning in early diagnosis of lung cancer .Methods Further screenings and assessments were carried out using low‐dose CT （40 mA ,30 mA and 20 mA） in 60 patients with lung mass discovered by standard‐dose CT （120‐200 mA） ,diagnostic accu‐racy rates of lung cancer added up respectively .Results Diagnostic accuracy rate of lung cancer by stand‐ard‐dose CT ,those of low‐dose CT of 40 mA ,30 mA and 20 mA were 75 .6% ,70 .3% and 55 .6% respec‐tively .There were no significant differences in diagnostic accuracy rates of lung cancer among low‐dose CT of 40 mA ,of 30 mA and standard‐dose CT （χ2 = 0 .12 ,0 .79 ,P〉 0 .05） and was a significant difference in that between low‐dose CT of 20 mA and standard‐dose CT （χ2 = 5 .09 ,P 〈 0 .05） .Conclusion Low‐dose spiral CT （30 mA） scanning has higher sensitivity and lower radiation ,could be used in the early screening of lung cancer .

作者王文杨劲松张志功刘建滨郭一清刘一骐

机构地区中南大学湘雅医学院湖南省人民医院心胸外科湖南省人民医院放射科

出处《临床心身疾病杂志》 CAS 2015年第5期5-7,共3页 Journal of Clinical Psychosomatic Diseases

基金湖南省科学技术厅科技计划项目（编号2013SK3197）

关键词低剂量螺旋CT 肺癌恶性肿瘤早期筛查早期诊断 Low-dose CT lung cancer malignant tumor early screening early diagnosis

分类号 R814.42 [医药卫生—影像医学与核医学]

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1Jemal A, Bray F, Ferlay J, et al. Global cancer statis tics[J]. CA Cancer J Clin,2011,61(2) :69.
2National Lung Screening Trial Research Team, Aberle DR, Adams AM, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening [J]. N Engl J Med, 2011,365:395.
3Yao Y, Fan Y, Wu J, et al. Potential application of non-small cell lung cancer-associated autoantibodies to early cancer diagnosis [J]. Biochem Biophys Res Commun, 2012, 423(3) ; 613.
4Aberte DR, Berg CD, Black WC, et al. The National Lung Screening Trial: overview and study design [J]. Radi- ology,2011, 258(1) :243.
5National Research Council. Health risks from exposure to low levels of ionizing radiation: beir VII-phase 2 [M]. Washington, DC: The National Academies Press, 2006.
6The 2007 Recommendations of the International Com- mission on Radiological Protection [J]. Ann ICRP,2007,37 (2--4) : 1.
7Kim YH, Lee KS, Primack SL, et al. Small pulmonary nodules on CT accompanying surgically resectable lung canc- er: likelihood of malignancy [J]. J Thorac Imaging, 2002, 17(1) :40.
8Jaklitsch MT, Jacobson FL, Austin JH, et al. The A- merican Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups [J]. J Thorac Cardiovasc Surg, 2012,144 (1) : 33.