不同浓度罗哌卡因用于阑尾炎手术腰硬联合麻醉效果比较

Effect Comparision of Different Concentrations of Ropivacaine for Combined Spinal Epidural Anesthesia in Appendicitis Operation

目的:探讨罗哌卡因用于阑尾炎手术腰硬联合麻醉时的最佳浓度。方法:88例阑尾炎手术患者随机分为A、B两组,分别使用0.5%和0.75%罗哌卡因行腰硬联合麻醉。比较两组患者平均动脉压和心率变化,感觉阻滞平面及范围、运动阻滞时间、患者对麻醉效果的满意度及其药品不良反应。结果:A组患者的平均动脉压和心率变化幅度明显小于B组(P<0.05);A、B两组患者对麻醉效果的满意度、感觉阻滞平面及范围比较,差异无统计学意义(P>0.05),A组的运动阻滞时间和药品不良反应发生率明显低于B组(P<0.05)。结论:0.5%罗哌卡因用于阑尾炎手术腰硬联合麻醉中效果较好,患者平均动脉压和心率变化幅度小,不良反应发生率低。

Objective： To study the best concentration of ropivacaine for combined spinal epidural anesthesia in the operation of appendicitis. Methods：88 cases of appendicitis patients were randomly divided into two groups A and B. They were given combined spinal epidural anesthesia with 0.5% and 0.75% ropivacaine respectively. The mean arterial pressure and heart rate, range sensory block, motor block time, the satisfaction of the effect of anesthesia, and the adverse drug reactions were eampared. Results： The scale of variation of mean arterial pressure and heart rate in the patients of group A were significantly less than those in group B （ P 〈 0.05 ）. The two groups of patients for surgery anesthesia satis- faction, the range sensory block and motor block had no significant difference （ P 〉 0.05 ）. The motor block time and the adverse drug reactions of group A were significantly lower than that of patients in group B （ P 〈 0.05 ）. Conclusion： The effect of 0.5% ropivacaine used on combined spinal epidural anesthesia with appendicitis operation is good. The amplitude of variation of mean arterial pressure and heart rate of patients is small. And the adverse reactions is low.