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腹膜透析相关性腹膜炎的致病菌及其耐药性分析 被引量:7

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摘要 目的探讨腹膜透析相关性腹膜炎的病原菌分布及其耐药性变化情况,以指导临床治疗。方法回顾性分析我院62例次腹膜透析相关腹膜炎患者的一般情况、细菌培养、药敏试验、疗效及转归,并进行统计学分析。结果38例次培养阳性,总体培养阳性率为61.29%,其中G+菌17例次,G-杆菌16例次,真菌4例次,结核杆菌1例次。G+菌对苯唑西林、头孢唑林、克林霉素、环丙沙星耐药率较高,对利奈唑胺、万古霉素等的耐药率最低。G-菌中,所有菌株对碳青霉烯类、头孢哌酮舒巴坦敏感。而对氨苄西林、头孢曲松、头孢噻肟的耐药率较高。G+菌、G-菌、培养阴性腹膜炎患者治愈率分别为82.35%、75.00%、70.83%;真菌及结核杆菌感染的腹膜炎患者均拔管。结论尽早诊断、及时治疗对腹膜炎的预后有较大影响,尽量提高腹膜透析液细菌培养阳性率有助于腹膜透析相关性腹膜炎的治疗,减少耐药菌感染的发生。
出处 《临床内科杂志》 CAS 2015年第8期553-555,共3页 Journal of Clinical Internal Medicine
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