静心电针法治疗围绝经期综合征临床研究

Clinical Study on Therapeutic Effect of "Ataraxia Electroacupuncture" on Perimenopausal Syndrome

目的:观察静心电针法治疗围绝经期综合征的临床疗效。方法:将符合标准的围绝经期患者60例随机分为治疗组(30例)和对照组(30例)。治疗组给予静心电针法治疗,对照组给予克龄蒙治疗,均治疗3个周期。分别于治疗前、治疗1个月、治疗3个月(即治疗结束)、治疗后3个月及治疗后6个月进行随访,采用改良的Kupperman指数(KI)进行症状评分,并于治疗前、治疗结束各检测1次血清雌二醇(E2)、卵泡刺激素(FSH)、黄体生成激素(LH)。结果:治疗组和对照组的总有效率比较差异无统计学意义(90.00%vs.93.33%,P>0.05)。2组KI评分,治疗后各时间点与治疗前比较差异均有统计学意义(P<0.01),2组之间各时间点差异无统计学意义(P>0.05),2组在治疗期间,KI均有下降,当治疗结束后3个月与6个月时,KI评分稍有上升,对照组上升稍多,但2组之间差异无统计学意义(P>0.05)。2组治疗后,性激素水平均得到改善(P<0.01),但2组之间差异无统计学意义(P>0.05)。结论:静心电针法治疗围绝经期综合征,安全、疗效好,值得推广应用。

Objective：To observe the curative effects of ＂ataraxia electroacupuncture＂ on perimenopausal syndrome （PMS）. Methods：60 cases of PMS were randomly divided into a treatment group and a control group ,30 cases in each group. The treatment group were treated with ＂ataraxia electroacupuneture＂ and the control group with oral administration of Climen tablets for 3 courses of the treatment. The therapeutic effects and changes of scores of Kupperman index （KI） were investigated before and after treatment for 1 month, 3 month ,finished treatment for 3 month, and 6 month, and serum estradiol （E2）,follicle stimulating hormone （FSH） ,luteinizing hormone （LH） levels before and after treatment were observed. Results：The total effective rate was 90.00% in treatment group while 93.33% in control group ,with no significant difference between the two groups （P〉0.05）. After treatment,the scores of KI in every time point was significantly decreased （P〈0.01） ,but there was no significant difference between the two groups in the same time point （P〉0.05）. And the scores of KI were increased slightly in 3 month and 6 month after treatment, which was more clear in the control group, but there was no significant difference between the two groups （P〉 0.05 ）. And after treatment, serum E2, FSI-t and LH levels were all better than before treatment in both group （P〈 0.01 ）, but there were no significant differences between the two groups （P〉 0.05 ）. Conclusions： ＂Ataraxia electroacupuncture＂ is safe and effective for treatment of perimenopausal syndrome, and worth promoting.