水环境中萘普生共存物竞争光降解研究

Competition for light degradation of naproxen and its coexists

环境水样中污染物种类繁多,共存物自然转化相互竞争影响.通过优化色谱分离分析条件,建立萘普生色谱分析方法,考察各类共存物对萘普生自然光降解的影响.以呋喃唑酮为紫外吸收重叠共存物考察其对萘普生自然光降解的影响.实验结果显示,呋喃唑酮明显抑制萘普生光降解,说明具有紫外吸收重叠的共存物会发生竞争光降解.此外,分别选取了具有与萘普生260 nm处紫外吸收重叠的双氯芬酸钠、酮洛芬、吲哚美辛、依洛沙星和紫外吸收不重叠的布洛芬、甲硝唑作为共存物,考察其对萘普生自然光降解的影响规律.结果表明,具有不同结构及紫外吸收特征的化合物对萘普生自然光降解的影响不同,这些共存物和萘普生之间紫外吸收的重叠程度及吸收强度决定了共存物对萘普生自然光降解的抑制作用程度,抑制作用随紫外重叠的增加而增加.这种共存物及紫外吸收特征和其对萘普生的自然光降解抑制作用关系的竞争降解规律,是萘普生自然归趋研究的重要依据.

The effect of coexisting compounds on the fate of pharmaceuticals under solar irradiation wasinvestigated. Furazolidone with familiar absorption spectrum to NPX was employed to study the effect ofphotodegradation. The experimental results indicated that the presence of coexisting compounds with familisrabsorption spectrum to NPX could produce obvious effect on the photodegradation of NPX. Besides,theoverlapping absorption spectrum to NPX of 260 nm such as diclofenac sodium,ketoprofen,indometacin,enoxacin and the non- overlapping absorption spectrum ibuprofen and metronidazole were selected toinvestigate the mechanism of effect. The results showed that the effect depended on the degree of overlappingabsorption spectrum between NPX and the coexisting pharmaceuticals. The relationship between the degree ofthe influence and the ultraviolet absorption spectra of coexisting pharmaceuticals found in this study could givean example in assessing the fate of pharmaceuticals in environmental water.