摘要
目的探讨颅脑创伤后肺部感染的危险因素，指导临床疗效。方法回顾性分析2014年1月-2014年6月收治的325例颅脑创伤患者的临床资料，其中男198例，女127例；年龄11—78岁[（38．4±8．3）岁]。致伤原因：交通伤172例，高处坠落伤80例，殴打伤56例，其他17例。总结肺部感染情况，分析其危险因素。结果32例（9．8％）发生肺部感染，铜绿假单胞菌最常见，共12株。单因素分析结果显示，机械通气、开放气道、误吸与肺部感染的发生密切相关；Logistic回归分析提示误吸（OR=2．891，P〈0．05）、机械通气（OR=1．323，P〈0．05）为其独立危险因素。结论肺部感染是颅脑创伤患者的严重并发症之一，危险因素主要包括误吸、机械通气等，应积极预防和治疗，降低其发生率，争取患者获得最佳的治疗效果。
Objective To determine the incidence of lung infection and associated factors in patients with traumatic brain injury for the sake of improving the clinical outcomes. Methods A retrospective analysis was made on records of 325 patients who hospitalized between January 2014 and June 2014. There were 198 male and 127 female patients, aged 11 -78 years [（38.4 ± 8.3） years]. A total of 172 patients were injured in traffic accidents, 80 in high falls, 56 in blow accidents, and 17 in others. Lung infection status was documented and related risk factors were analyzed. Results Thirty-two patients （9. 8% ） had lung infection. Pseudomonas aeruginosa amounting to 12 strains was the most common pathogenic bacteria. Univariate analysis showed mechanical ventilation, airway open, and aspira- tion were significantly related to lung infection. Logistic regression identified aspiration （ OR = 2. 891, P 〈 0.05 ） and mechanical ventilation （ OR = 1. 323, P 〈 0.05 ） as the independent risk factors for lung infection. Conclusions Lung infection is a serious complication of traumatic brain injury, affected largely by aspiration and mechanical ventilation. Active preventions, reductions of risk factors, and early treatments should be clone to get the best efficacy.
出处
《中华创伤杂志》
CAS
CSCD
北大核心
2015年第9期820-822,共3页
Chinese Journal of Trauma
关键词
颅脑损伤
感染
肺炎
危险因素
Craniocerebral trauma
Infection
Pneumonia
Risk factors
