期刊文献+

卵巢无性细胞瘤临床病理分析并文献复习 被引量:8

Clinicopathological features of ovarian dysgerminoma and literature review
下载PDF
导出
摘要 目的:探讨卵巢无性细胞瘤的临床病理学特点及诊断要点。方法:对2例无性细胞瘤进行临床资料、病理形态学及免疫组化观察,并结合文献对其诊断及鉴别诊断进行探讨。结果:镜下肿瘤细胞被窄的纤维组织分隔呈巢状、岛屿状、条索状,纤维隔内有多少不等的淋巴细胞浸润,瘤细胞与核的大小外观呈明显一致性,胞质丰富淡染,核大圆形,核仁明显,核分裂像易见。免疫组化示肿瘤细胞PLAP呈不同程度阳性。结论:掌握无性细胞瘤的病理特点,提高对无性细胞瘤的认识,对避免误诊是至关重要的。 Objective: To investigate and discuss the clinicopathological features, diagnosis of ovarian dysgerminoma. Methods: By analysis the features of clinicopathology and immunohistochemistry of 2 cases, and combining together the review of the literatures.Results: The microscopic tumor cell nests can be separated by narrow fibrous tissue, islands, funicular, fibre separated with varying amounts of lymphocyte infiltration, the obvious appearance of the size of the tumor cells and nuclear is consistency, cytoplasmic rich light dye, nuclear big round, obvious nucleoli, nuclear fission as easy to see. Positive immunohistochemical PLAP show varying degrees of tumor cells.Conclusion:It is essential to grasp the pathological characteristics of ovarian dysgerminoma and enhance awareness so as to avoid misdiagnosis.
出处 《临床与病理杂志》 CAS 2015年第8期1585-1590,共6页 Journal of Clinical and Pathological Research
关键词 无性细胞瘤 卵巢 病理学 临床 免疫组化 dysgerminoma ovarian pathology clinic immunohistochemistry
  • 相关文献

参考文献13

  • 1Meyer W. Is cancer a systemic disease?[J]. Ann Surg, 1931, 93(1): 35-39.
  • 2Hyseni N, Llullaku S, Jashari H, et al. Advanced ovarian dysgerminoma infiltrating both ovaries and uterus in a 7-year-old girl[J~. Case Rep Oncol Med, 2014, 2014: 910852.
  • 3Roberts OA, Oranye BC. Ovarian dysgerminoma in an adolescent: a case report[J]. AfrJ Meal Med Sci, 2013, 42(2): 197-200.
  • 4周徽,张阳德,石凯,肖瑶,郭嘉.少女卵巢无性细胞瘤的诊断与治疗[J].中国现代医学杂志,2014,24(32):110-112. 被引量:5
  • 5Ajao M, Vachon T, Snyder P. Ovarian dysgerminoma: a case report and /iterature review[J]. Mil Ivied, 2013, 178(8): e954-e955.
  • 6Ulbright TM. Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues[J], Mod Pathol, 2005, 18 Suppl 2: $61-$79.
  • 7Chen VW, Ruiz B, KiUeen JL, et al. Pathology and classification of ovarian tumors [J]. Cancer, 2003, 97(10 Suppl): 2631-2642.
  • 8Boran N, Tulunay G, Caliskan E, et al. Pregnancy outcomes and menstrual function after fertility sparing surgery for pure ovarian dysgerminomas [J]. Arch Gynecol Obstet, 2005, 271 (2): 104-108.
  • 9戴莉萍,徐国萍.卵巢无性细胞瘤6例临床病理分析[J].中国医药导刊,2010,12(3):382-383. 被引量:12
  • 10周亦文,骆利康,申华峰.30例卵巢无性细胞瘤临床病理分析[J].肿瘤学杂志,2008,14(6):494-495. 被引量:8

二级参考文献22

  • 1范懿隽,周家德.卵巢无性细胞瘤的临床特点及预后影响因素[J].安徽医科大学学报,2007,42(2):215-218. 被引量:18
  • 2卢金镶,申培红,张全武.卵巢无性细胞瘤PLAP、NSE和PRL检测的临床意义[J].医药论坛杂志,2007,28(8):48-49. 被引量:5
  • 3范琅娣.卵巢临床与病理[M].天津:天津科学技术出版社.1993,251-256.
  • 4Reddy KB,Ahuja VK,Kannan V, et al.Dysgerminoma of the ovary:a retrospective study[J].Australas Radiol, 1997;41:262-265.
  • 5Tatekawa Y, Kemmotsu H,Mouri T, et al.A case of pediatric ovarian dysgerminoma associated with high serum levels and positive immunohistochemical staining of neuron-specific enolase[J].J Pediatr Surg,2004;39(9):1437-1439.
  • 6回允中主译.外科病理鉴别诊断学[M].北京:清华大学出版社,2004:253.
  • 7田杨顺.妇科肿瘤临床病理学[M].北京:人民卫生出版社,2001:252-253.
  • 8刘彤华.诊断病理学[M].北京:人民卫生出版社,2006:350—354.
  • 9Chen VW, Ruiz B, Killeen JL, et al. Pathology and classification of ovarian tumors[J]. Cancer, 2003, 97(Suppl 10): 2631-2642.
  • 10张蓉 洪婉君 李淑敏 等.卵巢无性细胞瘤60例临床叫顾分析.中华妇产科杂志,1999,15(5):303-304.

共引文献21

同被引文献29

  • 1范懿隽,周家德.卵巢无性细胞瘤的临床特点及预后影响因素[J].安徽医科大学学报,2007,42(2):215-218. 被引量:18
  • 2卢金镶,申培红,张全武.卵巢无性细胞瘤PLAP、NSE和PRL检测的临床意义[J].医药论坛杂志,2007,28(8):48-49. 被引量:5
  • 3应艳琴,罗小平.性发育障碍的诊断与鉴别程序[J].临床儿科杂志,2007,25(12):965-970. 被引量:6
  • 4A L Husaini,Soudy H,EI Din Darwish A,et al.Pure dysgerminoma of the ovary:a single institutional experience of 65patients[J].Med Oncol,2012,29(4):2944-2948.
  • 5Ajao M,Vachon T,Snyder P.Ovarian dysgerminoma:a case report and literature review[J].Mil Med,2013,178(8):e954-e955.
  • 6Gueeriero S,Testa AC,Timmerman D,et al.Imaging of gynecological disease⑹:clinical and ultrasound characteristics of ovarian dysgerminoma[J].Ultrasound Obstet Gynecol,2011,37(5):596-602.
  • 7郑杰等译.Rosai&Ackerman外科病理学[M].第十版.北京:北京大学医学出版社,2014,1583-1584.
  • 8回允中等译.妇科病理学图谱[M].第二版.北京:人民卫生出版社,2011,339-342.
  • 9刘彤华,李维华,刘鸿瑞,等.诊断病理学[M].第三版.北京:人民卫生出版社,2013,629.
  • 10武忠弼等译.里德病理学[M].第五版中文版.上海:上海科技出版社,2007.796.

引证文献8

二级引证文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部