研究儿童接种乙型肝炎疫苗预防效果

Study of Vaccinating Children Against Hepatitis B Prevention Effect

目的研究分析儿童接种乙型肝炎疫苗的预防效果。方法选乙型肝炎疫苗接种的儿童100例,测定各个年龄阶段儿童的乙型肝炎抗体和抗原。结果 100例儿童中产生免疫应答的有72例,占72%,无应答的有28例,占28%,并且抗体浓度随着年龄的增长而降低;同时,不同性别乙型肝炎疫苗接种情况,比较无显著差异不具统计学意义(P>0.05)。结论对儿童进行乙型肝炎疫苗接种是非常必要的,能有效保障儿童健康安全,但抗体浓度随着年龄的增长而降低,所以对年龄偏大的儿童应加大疫苗剂量,从而提高应答率。

ObjectiveTo study the analysis of vaccinating children against hepatitis B prevention effect.MethodsChoose 100 cases of hepatitis B vaccination of children, the determination of al ages children＇s hepatitis b antibody and antigen.Results 100 cases of immune response in children with 64 cases, accounting for 64%, no answer in 36 cases, accounted for 36%, and the antibody concentration and decreased with age; At the same time, the different sex hepatitis B vaccination, is no significant difference of no statistical significance （P〉 0.05）.Conclusion Hepatitis B vaccination of children is very necessary and effective to ensure the safety of children＇s health, but the antibody concentration and decreased with age, so the older children should increase the vaccine dose, so as to improve response rates.