不同内镜下注射治疗消化道溃疡出血的疗效比较

Comparison of Different Endoscopic Injection Treatment of Peptic Ulcer Hemorrhage

目的：探讨不同内镜下注射不同药物治疗消化道溃疡出血的疗效。方法收集2013年2月-2015年3月我院消化科收治的急诊行胃镜下止血的消化道溃疡出血的患者132例，根据注射药物的不同分为三组，肾上腺素组（46例）、去氨加压素组（42例）和硬化剂组（44例），内镜下止血后比较三组的首次止血成功率、再出血率、外科手术率、止血时间、住院天数。结果三组间首次止血成功率、外科手术率、住院天数间的差异无显著性（P〉0.05）；硬化剂组的再出血率为11.4%，止血时间为（10.1±0.3）h，均优于去氨加压素组和肾上腺组，差异具有统计学意义（P 〈0.05）。结论内镜下进行药物注射止血疗效确切，能够有效控制出血减少外科手术率，其中以注射硬化剂疗效最为显著。

ObjectiveTo investigate the endoscopic injection of different medications peptic ulcer hemorrhage.MethodsOf patients from February 2013 to March 2015 at our hospital gastroenterology bleeding admitted to the emergency line gastroscopy ulcer bleeding 132 cases, depending on the injection of drugs into three groups, epinephrine group （46 cases）, desmopressin group （42 cases） and hardener （44 cases）, bleeding after endoscopic hemostasis first three groups of success rate, rebleeding, surgery rates, bleeding time, length of hospital stay.Resultsfor the first time to stop bleeding among the three groups success rate, surgery rates, the difference length of stay between the no significant （P〉 0.05）; hardener rebleeding rate of 11.4%, bleeding time was （10.1 ± 0.3） , were significantly better than desmopressin group and adrenal group, the difference was statisticaly significant （P 〈 0.05）. Conclusion Endoscopic injection hemostasis exact efficacy of drugs, can effectively control bleeding rate reduction surgery, in which the injection sclerotherapy most significant effect.