针刺治疗功能性消化不良机制研究进展

Research progress of mechanism of functional dyspepsia treated with acupuncture

通过检索中国知网、万方数据库、PubMed近5年关于针刺治疗功能性消化不良的文献,整理及归纳其研究成果以探讨针刺治疗功能性消化不良的机制。结果发现,针刺可以调节脑肠肽的分泌,引起边缘系统——大脑的协同响应,对大鼠血清分子代谢物、调节信号转导通路中的基因表达有调节作用。认为针刺治疗功能性消化不良的机制是多途径的,而调节脑肠轴的功能活动是其中一个重要机制。

Literature about functional dyspepsia treated with acupuncture in recent 5years is retrieved in China National Knowledge Infrastructure（CNKI）,Wanfangdatabase and PubMed.The research achievements are arranged and summed up to explore the mechanism of acupuncture for functional dyspepsia.It is found that acupuncture can regulate the secretion of braingut petide,and cause the coordination response of limbic system-brain.Also,it adjusts serum molecule metabolin and the gene expression of the transduction pathway of adjustment signal for rats.It is believed that functional dyspepsia treated with acupuncture is through multiple ways,and adjusting the function of braingut axis is one of the important mechanisms.