长效干扰素抗病毒治疗慢性乙型肝炎的不良反应及护理对策

Side effects and nursing strategies of long acting interferon in the treatment of chronic hepatitis B

目的通过观察慢性乙型肝炎长效干扰素抗病毒治疗的不良反应，探讨减少不良反应的护理对策，以提高疗效。方法对78例使用长效干扰素抗病毒治疗的慢性乙型肝炎患者进行前瞻性研究，观察用药期间出现的不良反应，实施针对性强、有效的护理措施。结果78例患者均发生了不同程度的不良反应，一例发生甲状腺功能亢进（甲亢）中止治疗，其余77例通过护理，均安全用药，顺利完成治疗。结论应用长效干扰素期间，要重视不良反应的观察及护理；加强心理护理，将之贯穿整个疗程是保证疗效的关键。

Objective To investigate the side effect of long acting interferon in the treatment of chronic hepatitis B, and to explore the nursing strategies to reduce the side effects and improve curative effect. Methods 78 chronic hepatitis B patients with long acting interferon for treatment were given prospective study; they were observed the side effects of the drug, and given the targeted, effective nursing measure. Results 78 cases of patients occurred different degrees of side effects, a case discontinued treatment because of hyperthyroidism, and the remaining 77 cases were all through the nursing with safe medication, and completed the treatment successfully. Conclusion It should be pay attention to observe and nurse the side effects, strengthen psychological care, during the application of the long-term interferon. Run through it for the whole course of treatment is the key to the treatment.