期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

聚酰胺-胺树枝状聚合物诱导牙体组织仿生矿化的研究现状

Polyamidoamine( PAMAM) dendrimer induces tooth organizations biomimetic mineralization: A review
下载PDF
导出
摘要 利用生物材料诱导牙体组织仿生矿化,从而实现牙体缺损的自愈性修复一直都是口腔医学研究的目标之一。聚酰胺-胺树枝状大分子(polyamidoamine dendrimer,PAMAM)作为一种新型高分子纳米材料,因其具有独特的性质而成为仿生矿化领域的研究热点。本文就PAMAM诱导牙体组织仿生矿化的理论背景及其研究现状作一综述。 Polyamidoamine（ PAMAM） is a new type of polymer nano- materials. Because of its unique nature,it has been a hot topic in biomimetic mineralization research field. In this review,the structure and the mechanisms of PAMAM- induced biomimetic mineralization of tooth hard tissues are summarized.
作者 谢方方 韦小浪
机构地区 广西医科大学附属口腔医院
出处 《牙体牙髓牙周病学杂志》 CAS 2015年第8期505-509,共5页 Chinese Journal of Conservative Dentistry
基金 广西自然科学基金(2011GXNSFA01829) 广西高校科学技术研究一般项目(2013YB056) 广西医疗卫生适宜技术研究开发项目(S201305-01)
关键词 聚酰胺-胺 羟基磷灰石 仿生矿化 polyamidoamine（PAMAM） hydroxyapatite（HA） biomimetic mineralization
分类号 R783.1 [医药卫生—口腔医学]
  • 相关文献

参考文献26

  • 1Svenson S, Tomalia DA. Dendrimers in biomedical applications - re- flections on the field[ J ~. Advanced drug delivery reviews, 2005, 57 (15) :2106 -2129.
  • 2Tomalia DA,Baker H, Dewald JR,et al. A new class of poly- mers: starbumt - dendritic macromolecules[ J]. Polym J, 1985, 17(1) :117 -132.
  • 3Eichman JD, Bielinska AU, Kukowska - Latallo JF, et al. The use of PAMAM dendrimers in the efficient transfer of genetic ma- terial into ceils [ J ]. Pharm Sci Technolo Today, 2000, 3 ( 7 ) : 232 - 245.
  • 4Moradian-Oldak J. Amelogenins: assembly, processing and con- trol of crystal morphology [ J ]. Matrix Biol, 2001, 20 ( 5/6 ) : 293 - 305.
  • 5Malik N, Wiwattanapatapee R, Klopsch R, et al. Dendrimers : relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 1251 -labelled poly- amidoamine dendrimers in vivo [ J ]. J Control Release, 2000, 65 (1/2) :133 - 148.
  • 6Ottaviani MF, Montalti F, Turro NJ, et al. Characterization of starburst dendrimers by the EPR technique. Copper ( II ) ions binding full generation dendrimers[ J]. J Phys Chem B, 1997, 101 (2) :158 - 166.
  • 7Moradian-Oldak J. Protein-mediated enamel mineralization [ J ]. Front Biosci, 2012, 17 : 1996 - 2023.
  • 8Du C, Falini G, Fermani S, et al. Supramoleeular assembly of amelogenin nanospheres into birefringent mieroribbons [ J 1. Scl- ertce, 2005, 307(5714) :1450 - 1454.
  • 9Iijima M , Hayashi K, Moriwaki Y. Effects of the Ca2 ~ and PO43- ion flow on the lengthwise growth of octacaleium phos- phate in a model systerm of enamel crystal formation with, con- trolled ionic diffusion [ J ]. J Cryst Growth, 2002, 234 ( 2/3 ) : 539 - 544.
  • 10Kawasaki K, Ruben J, Stokroos I, et al. The remineralization ofEDTA-treated human dentine[J]. Caries Res,1999, 33(4) : 275 - 280.

二级参考文献10

  • 1Brannstrom M. Sensitivity of dentine[J]. Oral Surg Oral Med O- ral Pathol,1966, 21(4) :517 -526.
  • 2Tomalia DA, Baker HA, Dewald J, et al. A new class of polymers starburst dendritic macromolecules[J]. Polymer J, 1985 , 17(1) :117 -132.
  • 3Chen H, Banaszak Holl M, Orr BG, et al. Interaction of dendrimers (artificial proteins) with biological hydroxyapatite crystals[J].J Dent Res, 2003,82(6) :443 -448.
  • 4Zhuo HZ, Zhuo PL, Yang SP, et al. Controlloble synthesis of hydroxyapatite nanocrystals via a dendrimer- assisted hydrothermal process[J]. Mater Res Bull,2007 ,42(9) :1611 -1618.
  • 5Chen L, Liang K, Li J, et al. Regeneration of biomimetic hydroxyapatite on etched human enamel by anionic PAMAM template in vitro[J]. Arch Oral Bioi, 2013,58(8) :975 -980.
  • 6Wu D, Yang J, Li J, et al. Hydroxyapatite-anchored dendrimer for in situ remineralization of human tooth enamel[J]. Biomaterials ,2013 ,34(21 ) :5036 - 5047.
  • 7王天达,王磊,冯海兰.聚酰胺-胺型树枝状分子对牙本质小管的封闭作用[J].中华口腔医学杂志,2012,47(z1):153-157.
  • 8LiJ , Yang J, Li J, et al. Bioinspired intrafibrillar mineralization of human dentine by PAMAM dendrimer[J]. Biomaterials, 2013 ,34(28) :6738 -6747.
  • 9Zhang X, Neoh KG, Lin CC, et al. Remineralization of partially demineralized dentine substrate based on a biomimetic strategy[J].J Mater Sci Med, 2012, 23 (3) : 733 -742.
  • 10刘彦,谢方方.树枝状聚合物诱导牙釉质仿生再矿化的体外实验研究[J].临床口腔医学杂志,2013,29(4):206-208. 被引量：4

共引文献1

牙体牙髓牙周病学杂志
2015年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部