补肾活血法改善子宫内膜异位症术后患者生存质量随机对照研究

Randomized Control Study of Invigorating Kidney and Promoting Blood Circulation in Improvement of Life Quality of Endometriosis

目的:观察补肾活血法对肾虚血瘀型子宫内膜异位症患者术后生存质量的改善情况。方法:选取95例子宫内膜异位症保守术后患者,随机分为空白组、中药组、西药组,治疗后运用世界卫生组织生存质量简化量表评价其生存质量改善情况,观察至术后2年,评估其远期生存质量情况。结果:中药治疗组整体生存质量、健康状况评价、生理领域、自我评价均改善(P<0.05);西药治疗组整体生存质量差异有统计学意义(P<0.05)。两者之间相比差异不明显(P>0.05),与空白组相比有统计学差异(P<0.05)。术后随访2年患者生存质量较同龄健康人在整体生存质量、生理领域、自我评价方面有下降(P<0.05)。结论:术后予中药补肾活血法可以提高子宫内膜异位症患者的生存质量。

Objective：To observe the effect of Chinese medicine treatment on the quality of life of kidney-deficiency and blood-stasis endometriosis patients. Methods：A total of 95 patients were randomized into blank group,Chinese medicine group,and western medicine group. Evaluation of WHOQOL-BREF scale was used to analyze changes of quality of life of these three groups. Results：After treatment,overall evaluation of quality of life,over all assessment of health status,physical field,and self-evaluation difference among Chinese medicine group were statistically significant（P〈0.05）,while overall evaluation of quality of life among western medicine group was statistically significant（P〈0.05）. There was no significant difference between Chinese medicine group and western medicine group（P〉0.05）,with significant difference compared to blank group（P〈0.05）. Overall evaluation of quality of life,physical field,and self-evaluation were statistically significant between healthy people and endometriosis patients in two years after surgery（P〈0.05）.Conclusion：Chinese medicine treatment with invigorating kidney and promoting blood circulation can improve quality of life of endometriosis.