手术与保守治疗烟雾病患者预后比较的meta分析

Curative effect of moyamoya disease between surgery therapy and conservative treatment:a Meta analysis

目的:评价手术治疗与保守治疗烟雾病患者预后的优劣性。方法:检索中文数据库及外文数据库,纳入所有手术治疗与保守治疗烟雾病的随机对照试验。使用Revman 5.0软件完成相关手术指标的Meta分析。结果:此次纳入Meta分析的文献共9篇,其中英文3篇,中文6篇,共527例患者。Meta分析结果显示:手术组再出血以及再缺血发生率低于保守组;手术组临床症状好转优于保守组;手术组病死率与保守组相比差异无统计学意义。结论:手术治疗对烟雾病患者的预后优于保守治疗。

Objective：To compare the curative effect between surgery therapy and conservative treatment on patients with moyamoya disease. Methods：Computer retrieval Chinese and foreign database,including in all the randomized controlled trial between surgical treatment and conservative treatment of moyamoya disease,Revman 5. 0 software completing a Meta analysis of the operation indicators. Results：Nine references were included in the Meta analysis,3 articles in English and 7 articles in Chinese,a total of 527 patients. Meta analysis results showed that the incidence of re- bleeding and re- ischemic,surgical group is lower than the conservative group. In the aspect of clinical symptoms improved,the surgical group is higher than that of the conservative group. In terms of mortality,there was no statistically significant difference in the surgical and conservative group.Conclution：The prognosis of surgical treatment for patients with moyamoya disease is superior to conservative treatment.