解剖M型超声联合Tei指数评价肝硬化患者左心功能的临床研究

A clinical study on anatomic M-mode and Tei index in evaluating left ventricular with liver cirrhosis

目的:探讨解剖M型超声联合心肌做功指数(Tei指数)评价肝硬化患者左心功能的临床可行性。方法:选取正常组(Ⅰ组)20例,病例组30例,依据Child-Pugh评分分为Ⅱ,Ⅲ,Ⅳ组。采用常规超声心动图测定50例研究对象的左室射血分数(LVEF),舒张早、晚期血流峰值(E,A峰)及其比值(E/A)和E峰减速时间(EDT)。采用解剖M型超声测定50例研究对象的左室等容收缩时间(ICT)、等容舒张时间(IRT)及射血时间(ET)。结果:肝硬化患者左室Tei指数及等容收缩指数(ICT/ET)、等容舒张指数(IRT/ET)均高于对照组,差异有统计学意义;且Tei指数及其相关参数较传统心功能的评价指标更为敏感。结论:解剖M型超声联合Tei指数为临床提供了简便易行的评价肝硬化患者左心功能的新方法。

Objective：To discuss the feasibility of evaluating left ventricular with liver cirrhosis by anatomic M- mode and Tei index. Methods：To select thirty cases and twenty normal subjects;thirty cases were divided into three groups according to the Child- Pugh. To obtain left ventricular ejection fraction（ LVEF）,late flow peak（ E,A） and E / A ratio,E peak deceleration time（ EDT）. To measure isovolumic contraction time（ ICT）,isovolumic relaxation time（ IRT）,ejection time（ ET） of left ventricular with anatomic M- mode for all subjects. Results：There is a statistic difference between normal controls and cases in Tei index,isovolumetric contraction index（ ICT / ET） and isovolumetric diastole index（ IRT / ET）. and Tei index and related parameters are more sensitive than traditional indexes with conventional echocardiography. Conclusion：The anatomic M- mode and Tei index provide a new simple testing method for evaluating left ventricular with liver cirrhosis.