内镜下短期放置特制可回收防反流支架治疗贲门失弛缓症效果研究

Effect of endoscopic short-term placement of specially designed recyclable anti-reflux stent on cardia achalasia

目的研究在内镜下短期放置特制可回收防反流支架、气囊扩张两种方法对贲门失弛缓症的治疗效果。方法将82例贲门失弛缓症患者随机分为两组,各41例。对照组采用气囊扩张方法治疗,观察组采用内镜下短期放置特制可回收防反流支架治疗,对比两组近期疗效,并随访半年,观察远期效果。结果两组治疗1个月时,Parischa评分差异无统计学意义(P>0.05);治疗半年后,观察组Parischa评分低于对照组(P<0.01),生活质量GQOL-74评分高于对照组(P<0.01),观察组扩张成功率高于对照组(P<0.05)。结论采用内镜下短期放置特制可回收防反流支架治疗贲门失弛缓症效果显著,有助于改善患者远期疗效,值得临床推广应用。

Objective To explore the effects of short-term endoscopic placement of specially designed recyclable anti reflux stent and balloon expansion on cardia achalasia. Methods Eighty-two patients with cardia achalasia were randomly divided into two groups（ n =41in each group）. Patients in the control group were treated with balloon dilatation,and those in the observation group un- derwent treatment of endoscopic placement of specially designed recyclable anti-reflux stent. The therapeutic effects of the two groups were compared. A 6-month follow-up was also carried out for the long-term efficacy observation. Results Parischa assessments at the time of 1 month of treatment had no difference in terms of statistical significance （ P 〉 0.05）. However, 6 months after the treatment, the Parischa assessment scores in the observation group were lower （ P 〈 0.01 ）, the GQOL-74 scores were higher （ P 〈 0.01 ） and the success rate was higher than those of the control group （ P 〈 0.05 ）. Conclusion The endoscopic short-term placement of special- ly designed recyclable anti-reflux stent in the treatment of cardia achalasia has good effect,which can help to improve the long-term effi- cacy for patients and is worth clinical application.