广州市萝岗区体检人群糖化血红蛋白水平调查研究

STUDY ON THE LEVEL OF GLYCOSYLATED HEMOGLOBIN A1C IN PHYSICAL EXAMINATIONS OF POPULATION IN LUOGANG DISTRICT OF GUANGZHOU

目的研究广州市萝岗区体检人群糖化血红蛋白（Glycosylated Hemoglobin A1c,HbA1c）水平的分布情况。方法收集2014年1～12月在我院体检的4245例体检人员样本，应用全自动生化分析仪及其配套原装试剂（免疫比浊法）检测HbA1c（％）水平，分别按性别、年龄、HbA1c（％）参考值及2014年糖尿病诊断新标准对样本进行分组统计分析。结果广州市萝岗区体检人群糖化血红蛋白HbA1c（％）在不同性别和年龄的人群中的分布有显著性差异，尤其在〉40岁以后的年龄段。结论广州市萝岗区男性HbA1c总体水平均明显高于女性，且随着年龄的增长HbA1c水平增高，根据2014年新指南筛查出疑似糖尿病者增多，为糖尿病的早发现、早治疗以及减少并发症的发生提供了依据。

Objective To investigate the glycosylated hemoglobin A1c （HbA1c） in physical examination population in Luogang District of Guangzhou. Methods 4 245 individuals undergoing physical examination in our hospital from 2014 January to December were recruited into this study. HbA1c（ % ） level was detected by the auto- matic biochemical analyzer and supporting the original reagents （Immune turbidimetric method）, and the results were treated with statistical analysis including sex, age, the reference value of HbA1 c and the 2014 new criteria for diagno- sis of diabetes mellitus, separately. Results The distribution of HbA1 e （%） levels in the population in Luogang District of Guangzhou were significantly different in different genders and age groups, especially among those aged o- ver 40 years. Conclusion The HbA1 c level of males in Luogang District is siguificanfly higher than that of females. The HbA1 c level is increased with age. According to the new 2010 guidelines, the suspected diabetes increased in number, which has provided a basis for early detection and early treatment of diabetes so as to reduce the incidence of diabetes complications.