学龄前儿童间歇性哮喘缓解期治疗进展

The Treatment Progress of Intermittent Asthma in Remission Stage of Preschoolers

长期吸入糖皮质激素(ICS)是支气管哮喘长期控制的首选用药。学龄前儿童间歇性支气管哮喘发病率高,自然缓解率高,临床特征多变,需要个体化治疗,以达到最佳控制的目的。大部分哮喘儿童可以采用急性发作或有发作先兆的控制治疗方案,即间断高剂量ICS治疗或白三烯受体调节剂,必要时联合支气管舒张剂,取代长期低剂量ICS治疗学龄前间歇性支气管哮喘。

Daily inhaled eorticosteroids （ICS） is the primary drug to control asthma. Intermittent asthma with high incidence among preschoolers is featured with high probability of natural relief and variable clinical manifestations, suggesting that itneeds individualized treatment to better control asthma. An intermittent high- dose ICS or leukotriene receptor antagonist in response to symptoms, is an emerging strategy for contrel of intermittent asthma in acute attack or pre-attack, combined with bronchial dilation agent if necessary, to replace daily low-dose ICS treating intermittent asthma among preschoolers.