维生素A联合铁剂治疗学龄期青少年缺铁性贫血临床观察

Clinical Observation of Vitamin A Combined with Iron Regent Therapy on School-Age Adolescents with Iron Deficiency Anemia

目的探讨维生素A缺乏(VAD)在学龄期青少年缺铁性贫血(IDA)发病中的意义,观察维生素A联合铁剂治疗青少年IDA的疗效。方法将88例缺铁性贫血青少年随机分为观察组与对照组各44例,观察组予以琥珀酸亚铁+维生素A治疗,对照组则单用琥珀酸亚铁治疗,疗程2个月。观察比较两组的临床疗效,并分析血清维生素A水平与贫血程度的关系。结果 (1)随着贫血程度的加重,VAD发生率显著增加(P<0.05);(2)观察组治疗后的Hb、SF、SI、TIBC升高幅度明显大于对照组(P<0.05)。结论青少年缺铁性贫血常合并VAD存在,维生素A联合铁剂治疗青少年IDA效果明显优于单纯铁剂治疗。

Objective To investigate the significance of vitamin A deficiency（VAD） in school-ageadolescents＇ iron-deficiency anemia（IDA） and observe the clinical effect of Vitamin A combined with iron regent therapy. Methods The 88 cases of school-age adolescents with IDA were randomly divided into the control group（44 cases） and observation group（44cases）. The observation group was treated with ferrous succinate and vitamin A,the control group was treated with ferrous succinate alone, the course of treatment was for two months. The clinical effect of the two groups was observed,and the relationship betweenvitamin A level and dementia degree. Results（1） The rate of VAD was higher with increased dementia degree（P〈0.05）;（2） The rising range of HB, SF, SI and TIBC in treatment group were obviously higher than that in control group（P〈0.05）. Conclusion The adolescents with IDA usually accompany VAD. The effect of Thevitamin A combined with iron reagents in treatment of teenagers IDA showed better effect than iron reagents only.