14例食管癌放疗后复发再程放疗的疗效观察

Observation on the curative effect of recurrence of esophageal carcinoma after radiotherapy for 14 patients with esophageal carcinoma

目的：观察食管癌放疗后复发再程放疗的疗效。方法：对14例再程放疗的食管癌患者采用Varian 23EX电子直线加速器适形放疗,1.2Gy/次,2次/日,总剂量DT33~62Gy,放疗2~3周。结果：10例病变消退（8例食道黏膜恢复,2例癌性狭窄,采用球囊扩张扩大食道,可正常进食）,无效3例病灶扩大,1例发生呕血,死亡;未发生放射性脊髓炎,有不同程度放射性食管炎;1年存活率50.00%、2年存活率28.57%。结论：放疗后复发再程放疗,有助于消除食管癌复发症状,改善患者生存质量,安全可靠,但仍有部分患者难获显著疗效。

Objective ：To observe the efficacy of radiotherapy for recurrence of esophageal carcinoma after radiotherapy.Methods ： 14 cases of esophageal carcinoma were given re course radiotherapy, 1.2Gy/times, 2 times /day, the total dose was DT33 - 62Gy,and were given radiotherapy for 2 to 3 weeks.Results：10 cases were lesion regression （8 cases of esophageal mucosa recovery,2 cases of carcinoma of the esophagus, the use of balloon dilatation of the esophagus, can be normal eating）,3 cases were ineffective and the lesions were enlarged,and hematemesis death occurred in 1 cases. There was no radioactive spinal cord inflammation, there were different levels of radiation esophagitis; 1 year survival rate was 50%,2 year survival rate was 28.57%.Conclusion ：The recurrence of esophageal carcinoma after radiotherapy is helpful to eliminate the symptoms of esophageal cancer recurrence and improve the quality of life of patients,it is safe and reliable,but there are still some patients difficult to get a significant effect.