抗菌药物专项整治前后医院Ⅰ类切口围术期预防用药分析

Analysis of Perioperative Prophylactic Application of Antibiotics for Type I Incision in a Hospital before and after Specific Rectification

目的探讨抗菌药物专项整治前后,某三级甲等医院Ⅰ类切口手术围术期预防用药情况,为进一步加强管理提供依据。方法全样本抽取医院2011年和2013年第1季度甲状腺、乳腺及腹股沟疝3种Ⅰ类切口手术患者病历,对围术期预防用药情况进行分析。结果专项整治后,该院抗菌药物预防使用率由100.00%降至8.92%,药品选择合理率由0.61%升至21.43%,用药时机合理率由23.17%升至64.29%,使用疗程合理率由2.43%升至64.29%,联合用药合理率由40.85%升至100.00%,抗菌药物平均费用由(1 134.82±840.77)元降至(25.17±106.49)元。结论通过开展抗菌药物专项整治活动,对该院抗菌药物的合理应用具有显著促进作用,但距国家卫计委的要求仍有较大差距,需进一步加强Ⅰ类切口手术围术期预防使用抗菌药物的管理。

Objective To investigate the PerioPerative ProPhylactic aPPlication of antibiotics to tyPeⅠincision in a hosPital before and after sPecific rectification. Methods PerioPerative ProPhylactic aPPlication of antibiotics to all inPatients that received thyroid surgeries, breast surgeries or inguinal hernia surgeries in the first quarter of 2011 and 2013 was analyzed. Results After sPecific rectification,the ProPhylactic rate decreased from 100. 00% to 8. 92%;the rate of rational medication increased from 0. 61% to 21. 43%;the rate of rational administration time increased from 23. 17% to 64. 29% ;the rate of rational treatment course increased from 2. 43% to 64. 29%;the rate of rational drug combination increased from 40. 85% to 100. 00%;the average cost of antibiotics declined from （1 134. 82 ± 840. 77） yuan to （25. 17 ± 106. 49） yuan. Conclustion SPecific rectification activities have Played a significant role in Promoting the rational use of antibiotics in the hosPital,but such situation hasn＇t met the requirements of National Health and Family Planning Commission of the PeoPle＇s RePublic of China,so it is essencial to further strengthen the management of PerioPerative ProPhy-lactic use of antimicrobial.