中青年脑梗塞患者同型半胱氨酸、高敏C反应蛋白及纤维蛋白原检测的临床意义

Clinical Significance of Serum Level of Homocysteine,high-Sensitivity c-Reactive Protein,Fibrinogen in Middle-aged and Young Patients with Cerebral Infarction

目的探讨中青年脑梗塞患者的血浆中同型半胱氨酸(Hcy)、高敏C反应蛋白(hs-CRP)及纤维蛋白(Fbg)水平及临床意义。方法测定86例中青年脑梗塞患者和56例健康体检者血浆Hcy、hs-CRP及Fbg水平并进行统计学分析。结果中青年脑梗塞组的血浆Hcy、hs-CRP及Fbg水平水平较健康正常组明显上升(P<0.01),阳性检出率也高于健康正常组。结论 Hcy、hs-CRP及Fbg在中青年脑梗塞患者明显上升,可作为预测中青年脑梗塞发生、发展的敏感指标。

Objective To investigate the clinical value of serum homocysteine （ Hcy）, highsensitivity C-reactive protein （hs-CRP）and fibrinogen （Fbg）in middle-aged and young patients with cerebral infarction. Methods Hcy, hs-CRP and Fib levels were measured in 86 middle-aged and young patients with cerebral infarction as well as in56 controls. Results The levels of serum Hcy, hs-CRP and Fbg in middle-aged and young patients with Cerebral infarction were significantly higher than those in controls（ P 〈 0.01 ） , and positive rate were also higher than controls （P 〈 0. 01 ）. Conclusion Serum levels of Hcy, hs-CRP and Fbg increased obviously in middle-aged and young patients with cerebral infarction ,joint detection can be used as sensitive markers in predicting its development.