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慢性肾脏病矿物质和骨异常发病机制的研究进展 被引量:3

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摘要 慢性肾脏病-矿物质和骨异常是指由于慢性肾脏病肾功能不全导致的一组病理生理变化,临床表现为钙磷代谢紊乱、继发性甲状旁腺功能亢进、骨骼成分与结构的改变及软组织钙化.其发病机制主要有成纤维细胞生长因子23增多、Klotho蛋白下调、高磷血症、活性维生素D减少及甲状旁腺激素增多等。
出处 《国际泌尿系统杂志》 2015年第5期777-780,共4页 International Journal of Urology and Nephrology
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