乙醛酸法合成MHPA过程中反应条件对产品收率的影响

Influence of reaction conditions on yield of the product in the process of MHPA synthesis by glyoxylic acid and guaiacol

用乙醛酸和愈创木酚合成3-甲氧基-4-羟基-苯乙醇酸(MHPA),考察了不同温度、pH值以及助剂对乙醛酸的转化率和MHPA收率的影响,在较佳的实验条件下,MHPA的收率可达95%,乙醛酸的转化率可达66.7%。

Using glyoxylic acid and guaiacol as raw material,synthesized 3-methoxy-4-hydroxymandelic acid（MHPA）.Reviewed the effects of reaction temperature,pH value and additives on guaiacol＇s conversion rate and MHPA＇s yield.Under optimum laboratory conditions,the yield of MHPA was95%,and the conversion rate of guaiacol could be improved to 62%.