摘要
非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)发病率不断升高,对其发生、发展及防治研究变得极为迫切。近年来肠道菌群被认为是机体一个重要的"特殊器官",参与机体代谢及相关疾病的发生、发展,与NAFLD关系密切。本文就肠道菌群与NAFLD的关系研究进行综述。
Currently, the morbidity of nonalcoholic fatty liver disease (NAFLD) is increasing, so it is extremely pivotal to study the development, progression, prevention and treatment of NAFLD. Intestinal microbiota, as an important and special organ of the body, intimately participates in the metabolism of the body, and the development and progression of NAFLD as well. In this article, the correlation between intestinal microbiota and NAFLD is reviewed.
出处
《传染病信息》
2015年第4期200-202,206,共4页
Infectious Disease Information
基金
国家重点基础研究发展计划(973计划)项目(2012CB517501)
国家自然基金(81070322
81270491
81470840)
上海市科委课题(0914090350
10411956300)
中国肝炎防治基金(XJS20120501)
上海市卫生局百人计划(XBR2011007)
关键词
脂肪肝
肠杆菌科
生态失调
内毒素类
乙醇
fatty liver
Enterobacteriaceae
dysbiosis
endotoxins
ethanol