期刊文献+

双能X线吸收测量法在慢性脊髓损伤患者腰椎骨密度丢失评价中的应用 被引量:2

Dual-energy radiographic absorptiometry in estimation of bone loss of lumber vertebra in patients with spinal cord injury
下载PDF
导出
摘要 目的评价双能X线吸收测量法(DEXA)腰椎正位和侧位测定慢性脊髓损伤患者腰椎骨密度的价值。方法采用DEXA检测9例四肢瘫痪和6例截瘫患者正位及侧位腰椎和全髋关节骨密度。结果患者平均年龄是(35±15)岁(20-62岁),损伤时间为(57±74)个月(53-200个月)。腰椎侧位骨密度T评分和Z评分高于正位[T评分L2:(20.7±1.2)vs(0.0±1.4),P=0.01;L3:(20.9±1.6)vs(0.3±1.3),P=0.002;L2-L3:(20.8±1.3)vs(0.2±1.3),P=0.001;Z评分L2:(20.3±1.1)vs(0.2±1.2),P=0.05;L3:(20.6±1.3)vs(0.5±1.3),P=0.01;L2-L3:(20.4±1.1)vs(0.4±1.2),P=0.005]全髋关节T评分、Z评分[分别为(21.1±1.0)和(21.0±1.0)]和L2-L3腰椎侧位评分类似,而L2-L3腰椎正位评分维持不变。随脊髓损伤时间增加,腰椎侧位骨密度显著下降,而腰椎正位骨密度保持不变。结论 DEXA检测腰椎侧位骨密度能够准确反映脊髓损伤患者骨密度丢失情况,而腰椎正位骨密度检测不能准确反映骨密度丢失情况,可能会低估患者骨折发生风险。 【Objective】 To determine bone mineral density(BMD) of the L-spine by PA and lateral(LAT)dual-energy radiographic absorptiometry(DEXA) in patients with chronic spinal cord injury(SCI). 【Methods】Measurements of the PA and LAT L-spine and hip were performed in 15 patients with SCI(9 with tetraplegia and 6 with paraplegia). The DEXA(GE Lunar Advance DEXA) images were obtained using standard software. Results were reported as mean ± SD.【Results】 The mean age was(35 ± 15) years(range: 20-62 years),and the duration of injury was(57 ± 74) months(range: 53-200 months). T- and Z-scores for BMD were higher for the LAT L-spine than those for PA L-spine [T-scores for L2:(20.7 ± 1.2) vs(0.0 ± 1.4), P = 0.01;L3:(20.9 ± 1.6) vs(0.3 ± 1.3), P = 0.002;L2-L3:(20.8 ± 1.3) vs(0.2 ± 1.3), P = 0.001;Z-scores for L2:(20.3 ± 1.1)vs(0.2 ± 1.2), P = 0.05;L3:(20.6 ± 1.3) vs(0.5 ± 1.3), P = 0.01; L2-L3:(20.4 ± 1.1) vs(0.4 ± 1.2), P = 0.005].The T- and Z-scores for the total hip [(21.1 ± 1.0) and(21.0 ± 1.0), respectively] and L2-L3LAT L-spine demonstrated remarkable similarities, whereas the L2-L3PA L-spine scores were not reduced. Bone mineral density of the LAT L-spine, but not the PA L-spine, was significantly reduced with increasing duration of injury. 【Conclusions】 Individuals with SCI may have bone loss of the L-spine that is evident on LAT DEXA but may be misdiagnosed by PA DEXA which may lead to underestimation of the potential risk of fracture.
出处 《中国现代医学杂志》 CAS 北大核心 2015年第24期28-33,共6页 China Journal of Modern Medicine
关键词 脊髓损伤 截瘫 四肢瘫痪 骨密度 椎体 双能X线吸收测量法 骨质疏松 spinal cord injury paraplegia tetraplegia bone mineral density vertebral body dual-energy X-ray absorptiometry osteoporosis
  • 相关文献

参考文献5

二级参考文献87

共引文献48

同被引文献15

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部