再次经尿道膀胱肿瘤电切治疗非肌层浸润性膀胱癌患者临床疗效及复发情况分析

Transurethral Resection of Bladder Tumor Clinical Efficacy of Nnon-Muscle Invasive Bladder Cancer and Recurrence Analysis Again

目的 通过采用再次经尿道膀胱肿瘤电切术治疗非肌层浸润性膀胱癌来观察其临床疗效及对复发影响,从而为非肌层浸润性膀胱癌患者临床治疗方案选择提供重要参考信息。方法 按照随机数字表法将68例非肌层浸润性膀胱癌患者分组为对照组与观察组,分别为34例。对照组采用单次经尿道膀胱肿瘤电切术治疗;观察组采用经尿道膀胱肿瘤电切术治疗,并于术后4-6周再次行经尿道膀胱肿瘤电切术。2组患者术后均予以药物化疗治疗,比较2组临床疗效及复发率。结果治疗后,观察组治疗有效率为85.29%（29/34）明显高于对照组73.53%（25/34）（P〈0.05）;术后随访6-12个月,平均为（10.5±1.0）个月;观察组复发率与对照组比较有统计学差异（P〈0.05）。2组治疗后各项生活质量均较术前明显改善,且观察组各项生活质量改善优于对照组,差异具有统计学意义（P〈0.05）。结论 采用再次经尿道膀胱肿瘤电切术治疗非肌层浸润性膀胱癌患者可提高临床疗效,减少复发。

Objective By using again transurethral resection of bladder tumor treatment of non - muscle invasive bladder canc-er to clinical efficacy and effects on relapse and thus non - muscle invasive bladder cancer patients in clinical treatment programs choose to provide important reference information. Methods According to a random number table 68 cases of patients with non - mus-cle invasive bladder cancer group was the control group and the observation group were 34 cases. The control group using a single tran-surethral bladder tumor resection;observation group transurethral bladder tumor resection,and 4 to 6 weeks after surgery again tran-surethral resection of bladder tumor. Group 2 was treated with postoperative chemotherapy treatment. Comparison of the two groups of clinical efficacy and recurrence rate. Results After treatment,the observation group therapy effective rate 85. 29%（29 / 34）was sig-nificantly higher than 73. 53%（25 / 34）（P ﹤ 0. 05）;postoperative follow - up of 6 to 12 months,with an average of（10. 5 ± 1. 0） months;. observation group relapse rate compared with control group（P ﹤ 0. 05）After treatment,the quality of life compared with be-fore surgery significantly improved the quality of life and improve the observation group than the control group,with statistical signifi-cance,P ﹤ 0. 05. Conclusion Again using transurethral resection of bladder tumor treatment of non - muscle invasive bladder cancer patients can improve clinical outcomes and reduce recurrence.