奥美拉唑与泮托拉唑治疗消化性溃疡疗效比较

Comparative Research on Pepticulcer in Application of Omeprazole and Pantoprazole Sodium

目的为了对比奥美拉唑与泮托拉唑药物在治疗消化性溃疡方面的临床效果。方法回顾性总结我院收治的上消化道出血患者44例相关资料,随机分组治疗后按照疗效标准进行数据统计,最后通过统计学方法比较差异性。结果使用泮托拉唑的患者治疗后显效17例,有效5例,无效0例,总有效率为100%,明显高于使用奥美拉唑的患者治疗后的总有效率结果81.8%,差异具有统计学意义(P<0.05)。结论泮托拉唑在治疗消化性溃疡导致的上消化道出血方面具有优秀的临床疗效。

Objective：In order to compare and contrast the clinical effects to pepticulcer in using omeprazole and pantoprazole sodium.Methods We summarize retrospectively related data and materials of 44 patients who were in hospital for upper gastrointestinal hemorrhage.Participants were randomly assigned to accept treatment,and the statistics was collected according to curative effect.The differences can be made out through statistical methods.Results We found that there were 17 participants who had obvious and remarkable effect after using pepticulcer,and other five participants also had some effect.The total effective rate reached 100%,which was higher than matched group that used omeprazole whose effective rate was 81.8%.There is the statistical significance in the difference（P〈0.05）.Conclusion Pantoprazole sodium has apparent advantage in treating pepticulcer.