摘要
目的探讨纵膈子宫的女性患者经宫腔镜下子宫纵膈电切术后行IVF-ET的妊娠结局。方法本研究采用历史性队列研究方法,我院2008年1月-2013年12月,156名子宫纵膈的患者行宫腔镜下子宫纵膈电切术后行IVF-ET治疗,共258个周期,为研究组;对照组选取经宫腔镜检查子宫形态正常的行IVF-ET治疗的160名患者,共230个周期;对比分析研究组和对照组的IVF-ET妊娠结局。结果两组患者第一次鲜胚移植和综合的鲜胚冻胚移植周期中,两组的临床妊娠率、分娩率、流产率和异位妊娠率的差异比较无统计学意义(P>0.05);最终分娩获婴率比较,研究组足月分娩率低于对照组(21.2%vs 55.2%,P<0.05),早产率高于对照组(72.0%vs 36.6%,P<0.05),过早产两组比较差异无统计学意义(6.8%vs 8.2%,P>0.05)。结论子宫纵膈患者经宫腔镜下子宫纵膈电切术治疗后行IVF/ICSI-ET,最终的临床妊娠率、分娩率和与子宫形态正常者无差异,手术并不影响妊娠结局,但会引起妊娠后期的早产,需临床注意。
Objective To study the mediastinum uterus of female patients with mediastinum womb under hysterescopy cutting line after the pregnancy outcome of IVF - ET. Methods This research adopts the historical cohort study method, from January 2008 - December 2014, 156 patients with mediastinum uterus under hysteroscopy mediastinum cutting line after IVF - ET treatment, a total of 258 cycles, for the team; Normal control group selected by hysteroseopy examination uterus form lines of IVF - ET treatment of 160 patients, a total of 230 cycles; Comparative analysis research group and the control group of IVF - ET pregnancy outcome. Results Two groups of patients for the fast time fresh embryo transplantation and integrated fresh embryos frozen embryo transplantation cycle, two groups of clinical pregnancy rate, births, differences in the rates of miscarriage and ectopic pregnancy is no statistical significance （P 〉 0.05）; Final delivery for the infant rate comparison, the team full-term births is lower than the control group （21.2% vs 55.2%, P 〈 0.05）, premature birth rate is higher than the control group （72.0% vs 36.6%, P 〈 0.05）, premature birth is similar between the two groups have no statistical significance （6.8% vs 8.2%, P 〉 0.05）. Conclusion Patients with mediastinum uterus by hysteroscopy under treatment of mediastinum uterus electricity cut after IVF - ET, the final clinical pregnancy rate, births, and no difference with normal uterus shape, the operation does not affect the pregnancy outcome of IVF - ET, but will cause pregnancy in the late preterm births, clinical attention should be paid.
出处
《新疆医学》
2015年第8期1017-1020,共4页
Xinjiang Medical Journal
