盐酸利多卡因在数字化子宫输卵管造影中的作用

目的探讨盐酸利多卡因注射液(2%)在子宫输卵管造影中的作用。方法回顾性分析371例不孕者子宫输卵管造影的影像学表现及临床反应,其中261例在造影剂中加入盐酸利多卡因注射液,为实验组,110例未加盐酸利多卡因注射液,为对照组。结果实验组患者与对照组患者相比,其假阳性率显著减低,而且临床不良反应显著减轻(P<0.05)。结论盐酸利多卡因注射液在子宫输卵管造影中具有防止输卵管痉挛、减轻患者不良临床反应的作用,从而降低因痉挛而导致的假阳性率,对弥散没有影响。

Objective The aim of our study is to study the efficacy of applying lidocaine （2%） contrast dye mixture for pain relief when performing hysterosalpingography （HSG）. Methods Clinical datas and Imaging Findings of 371 patients who diagnosed as infertility and performed HSG were retrospectively studied, of which 261 patients underwent HSG with contrast agent mixed with Lidocaine （2%）. Results Contrast to the placebo groups,subjects receiving the contrast dye-lidocaine mixture had significantly less pain and lower false-positive rate（P〈0.05）. Conclusion Lidocaine can prevent fallopian tube spasm and provide better pain relief when used in HSG, which may lead to lower false-positive rate, and aslo makes no difference on the diffusion of contrast dye.