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毛囊形态发生的信号转导通路及相关因子研究进展 被引量：3

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摘要 哺乳动物的被毛由毛囊产生,而毛囊是皮肤重要而复杂的附属器官。毛囊形态发生开始于早期胚胎阶段,历经诱导期、器官发生和细胞分化三个主要阶段,由神经外胚层和中胚层相互作用发育而成[1]。
作者 胡慧艳 墨锋涛 贾青 陶文欢 赵思思
机构地区 河北农业大学动物科技学院 国家北方山区农业工程技术研究中心
出处 《黑龙江畜牧兽医》 CAS 北大核心 2015年第9期89-92,共4页 Heilongjiang Animal Science And veterinary Medicine
关键词 形态发生 信号转导通路 毛囊 相关因子 器官发生 哺乳动物 早期胚胎 细胞分化
分类号 S852.31 [农业科学—基础兽医学]
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参考文献13

  • 1SCHMIDT- ULLRICH R, PAUS R. Molecular principles of hair follicle induction and morpbogenesis [J ]. Bioessays, 2005, 27 (3):247-261.
  • 2ANDI T,REDDY S T, GADDAPARA T, et al. Wnt signals are re- quired for the initiation of hair follicle development[ J]. Dev Cell, 2002, 2(s) 643 - 653.
  • 3HUEKEN J, VOGEL R, ERDMANN B, et al. Beta - Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin[J]. Cell, 2001, 105(4) : 533 -545.
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  • 5OWENS P, BAZZI H, ENGELKING E, et al. Smad4 - dependent desmoglein - 4 expression contributes to hair follicle integrity [ J ]. Dev Biol, 2008, 322(1 ) : 156 - 166.
  • 6MECKLENBURG L. An overview On congenital alopecia in domestic animals[J]. Vet Dermatol, 2006, 17(6) : 393 -410.
  • 7LIN M H, LEIMEISTER C, GESSLER M, et al. Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair - shaft layers[ j]. Development, 2000, 127 ( 11 ) : 2421 - 2432.
  • 8CHEN D, JARRELL A, GUO C, ei al. Dermal β- catenin activity in response to epidermal Writ ligands is required for fihrobfast prolif- eration and hair follicle initiation [ J]. Development, 2012, 139 (8) : 1522 -1533.
  • 9SICK S, REINKER S, TIMMER J, et al. WNT and DKK determine hair foilicle spacing through a reaction - diffusion mechanism [ J ]. Science, 2006, 314(5804): 1447-1450.
  • 10TORNQVIST G, SANDBERG A, HAGGLUND A C, et al. Cyclic expression of Lhx2 regulates hair formation[ J ]. PLoS Genet, 2010, 6(4) : e1000904.

二级参考文献8

  • 1Botchkarev VA,Botchkareva NV,Sharov AA,et al.Modulation of BMP signaling by noggin is required for induction of the secondary (nontylotrich) hair follicles[].Journal of Investigative Dermatology.2002
  • 2Nishimoto M,Fukushima A,Okuda A,et al.The gene for the embryonic stem cell coactivator UTF1 carries a regulatory element which selectively interacts with a complex composed of Oct-3/4 and Sox-2[].Molecular and Cellular Probes.1999
  • 3Panteleyev AA,Jahoda CA,Christiano AM.Hair follicle predetermination[].Journal of Cell Science.2001
  • 4PARK G T,MORASSO M I.Bone morphogenetic protein-2 ( BMP-2 ) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes[].Nucleic Acids Research.2002
  • 5BELECKY-ADAMS T L,ADLER R,BEEBE D C.Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation[].Development.2002
  • 6Sato N,Leopold PL,Crystal RG.Induction of the hair growth phase in postnatal mice by localized transient expression of Sonic hedgehog[].The Journal of Clinical Investigation.1999
  • 7Jung,HS,Francis-West,PH,Widelitz,RB,Jiang,TX,Ting-Berreth,S,Tickle,C,Wolpert,L,Chuong,CM.Local inhibitory action of BMPs and their relationships with activators in feather formation: implications for periodic patterning[].Developmental Biology.1998
  • 8Noramly,S,Morgan,BA.BMPs mediate lateral inhibition at successive stages in feather tract development[].Development.1998

共引文献12

同被引文献44

引证文献3

二级引证文献13

黑龙江畜牧兽医
2015年 第9期

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