老年高血压患者并发进展性脑梗死血压波动及临床分析

Blood pressure fluctuations in the elderly patients with hypertension complicated with progressive cerebral infarction

目的探讨老年高血压并发进展性脑梗死患者的血压波动情况及其影响因素。方法选取2011年1月至2013年1月期间于我院就诊的高血压患者(对照组,60例)和高血压合并进展性脑梗死患者(观察组,60例),观察并比较2组血压波动情况及影响因素。结果观察组24 h收缩压、舒张压,白昼收缩压、舒张压及夜间收缩压、舒张压明显高于对照组(P<0.05或P<0.01)。Logistic回归分析结果显示,吸烟、血脂异常、动态动脉硬化指数(AASI)升高是高血压合并脑梗死的危险因素。结论高血压并发进展性脑梗死患者夜间收缩压、舒张压波动较大,AASI属于预测高血压合并脑梗死发生的有效指标。

Objective To study the blood pressure fluctuations and the clinical risk factors in the elderly patients with hypertension complicated with progressive cerebral infarction.Methods Sixty patients with hypertension（control group） and 60 patients with hypertension complicated with progressive cerebral infarction（observation group） from January2011 to January 2013 in our hospital were enrolled in this study.The blood pressure fluctuation and the influencing factors were analyzed and compared between the two groups.Results The levels of 24 h systolic pressure,24 h diastolic pressure,day systolic pressure,day diastolic pressure,night systolic pressure and night diastolic pressure in the observation group were significantly higher than those in control group（P〈0.05 or P〈0.01）.Logistic regression indicated that smoking,dyslipidemia,AASI were correlated to hypertension complicated with cerebral infarction.Conclusions The hypertension patients complicated with cerebral infarction are present significant blood pressure fluctuation.AASI may be an effective indicator for hypertension patients with cerebral infarction.