摘要
目的对比18氟-氟代脱氧葡萄糖正电子发射断层成像/计算机断层成像(18F-FDG PET/CT)及同期MRI图像,初步探讨18F-FDG PET/CT在前列腺癌的诊断及评价中的价值。方法选取15例经手术或穿刺活检取得病理结果,且在1个月内同时行MRI及18F-FDG PET/CT的前列腺癌患者(其中9例未经治疗),对其图像、随访结果进行回顾性分析。结果前列腺原发病灶在18F-FDG PET/CT图像上可表现为放射性摄取异常增高,平均最大标准化摄取值(SUVmax)5.7(3~10.4):治疗前患者18F-FDG PET/CT及MRI的阳性率分别为89%和100%,治疗后患者分别为20%和80%。对于前列腺外的复发或转移灶,18F-FDG PET/CT和MRI的阳性率分别为73%和27%。对于全部入组患者,18F-FDG PET/CT及MRI的总阳性率均为93%。对于前列腺邻近器官的浸润,18F-FDG PET/CT发现1例,MRI发现2例。结论18F-FDG PET/CT能够较好地显示未经治疗的前列腺癌原发病灶,肿瘤治疗会影响其FDG摄取。对前列腺癌淋巴结、骨骼、软组织等部位的转移灶显示率18F-FDG PET/CT优于MRI;但对肿瘤周围浸润的显示,MRI更具优势。
Objectine To investigate the potential value of the 18 F - FDG PET/ CT scan for the diagnosis of prostate cancer by comparing with the MRI. Methods Analysis the PET/ CT and the MRI images of 15 patients with prostate cancer confirmed by pathology retrospectively. All of the patients have undergone 18 F - FDG PET/ CT and MRI on 2 separate days within 1 month. Results Increased FDG uptake in the primary le-sions can be detected by the18 F - FDG PET/ CT：In the patients without therapy,the positive rate of the 18 F - FDG PET/ CT and MRI is 89% and 100% ,respectively;in the patients after treatments,the positive rate is 20% and 80% ,respectively. For the recurrence or metastases outside the prostate,the positive rate of the 18 F - FDG PET/ CT and MRI is 73% and 27% . The total positive rate of the 18 F - FDG PET/ CT and MRI is 93% . Local invasion was present in one case in 18 F - FDG PET/ CT image,which is observed in 2 cases by MRI image. Conclusion The result indicate 18 F - FDG PET/ CT can be a tool to show the primary lesion for the patients with prostate cancer. But the level of the FDG uptake can be influenced by therapy. 18 F - FDG PET/ CT can detect more metastases compared with MRI. But MRI has advantages over 18 F - FDG PET/ CT in detecting local invasion.
出处
《临床和实验医学杂志》
2015年第18期1491-1494,共4页
Journal of Clinical and Experimental Medicine
基金
医学影像科国家临床重点专科建设项目
