功能性消化不良患者对疾病的认知情况及其对生命质量的影响

Effects of cognitive factors on quality of life in patients with functional dyspepsia

对182例功能性消化不良（FD）患者进行功能性消化不良认知问卷调查、Nepean消化不良指数简表（NDI）调查,并进行相关性分析.结果显示FD患者的情绪（r=0.284,P=0.006）、患者认为躯体化症状是其他疾病（r=0.211,P=0.045）、患者认为自己得了癌症（r=0.217,P=0.039）3项内容均与NDI总体得分呈正相关.回归分析示FD患者的NDI总得分与其情绪（β=3.709,P=0.009）、对躯体化症状的认知（β=3.259,P=0.020）、是否需要住院治疗的认知（β=4.533,P=0.006）、能否接受服药的认知（β=-3.207,P=0.029）有关.提示FD患者的生命质量受其对疾病认知的影响,改变这些认知可能提高患者的生命质量.

One hundred and eighty two outpatients with functional dyspepsia （FD）were enrolled.The cognitive questionnaire and the short form Nepean Dyspepsia Index （NDI） were used for survey.Spearman analysis showed that the cognitions of symptoms affected by emotion （r =0.284,P =0.006）,somatisation symptoms induced by other diseases （r =0.211,P =0.045）,and fears of cancer （r =0.217,P =0.039） were positively correlated with NDI scores.Multiple linear regression analysis demonstrated that cognition of symptoms affected by emotion （β =3.709,P =0.009）,somatisation symptoms induced by other diseases （β =3.259,P =0.020）,need of hospitalization （β =4.533,P =0.006）,and need of medication for several years （fβ =-3.207,P =0.029） were associated with NDI scores.These results suggest that the quality of life might be effected by cognitive factors,and the correction of cognitive mistakes may improve quality of life of FD patients.