雷公藤多甙片联合口服中药治疗寻常型银屑病43例

Glucosidorum Tripterygll Totorum Tablets combined with Oral Chinese Herbal Medicine in Treating Psoriasis Vulgaris for 43 Cases

目的观察雷公藤多苷片加自拟方治疗寻常型银屑病的临床疗效。方法选取寻常型银屑病患者83例,采用随机数字表法分成两组。试验组采用雷公藤多苷片加中药方剂,观察组单纯口服雷公藤多苷片。治疗3个月后采用酶联免疫吸附试剂盒检测两组患者外周血IFN-γ、IL-2和IL-17、VEGF水平,观察临床疗效。结果试验组患者IFN-γ,IL-2、IL-17和VEGF的水平较观察组明显下降(P<0.05),试验组有效率显著高于对照组(P<0.01)。结论雷公藤合并本院自拟方剂对银屑病疗效较单一使用雷公藤效果更佳。

Objective To observe the clinical effect of Glucosidorum Tripterygll Totorum tablets combined with oral Chinese herbal medicine in treating psoriasis vulgaris. Methods 83 cases of patients with psoriasis vulgaris were randomly divided into two groups. The experimental group was treated with Glucosidorum Tripterygll Totorum tablets and oral Chinese herbal medicine, and the observation group was simply treated with Glucosidorum Tripterygll Totorum tablets. Three months after treatment, the levels of IFN-γ, IL-2 and IL-17 and VEGF were detected by ELISA kit, and the clinical effect was observed. Results The levels of IFN-γ, IL-2 and IL-17 and VEGF were significantly decreased in the experimental group（ P〈0.05）, and the efficiency of the experimental group was significantly higher than that of the control group（ P 〈0.01）. Conclusion The effect of Glucosidorum Tripterygll Totorum tablets combined with self-made prescription was better than.