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血管周围脂肪:一种新的脂肪组织 被引量:9

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摘要 血管周围脂肪(PVAT),即贴近血管外膜层的脂肪组织,主要由脂肪细胞、成纤维细胞、干细胞、肥大细胞以及神经细胞等构成。除脑血管外,全身各处血管(大到主动脉,小到真皮层微血管)周围都存在脂肪细胞。早在2005年,发表于《柳叶刀》上的一篇文章中提出,PVAT是联系内脏脂肪、胰岛素抵抗以及血管疾病的重要枢纽,在肥胖相关性疾病中起到重要作用。由于PVAT所处部位的特殊性,它既有内脏脂肪的功能,可分泌大量脂肪因子及细胞因子,同时它又可以通过多种途径调节血管的功能。本文将对PVAT的功能研究进展作一简介。
出处 《中华糖尿病杂志》 CAS CSCD 2015年第8期518-520,共3页 CHINESE JOURNAL OF DIABETES MELLITUS
基金 国家自然科学基金项目(81173626) 广东省教育部产学研结合项目(20118090400379) “新世纪优秀人才计划”(NECT-11-0916)
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