Measuring effects of different noises in a model using ISI-distance methods

This paper examines the effects of current and conductance noises in a minimal Hodgkin- Huxley type model of a cold receptor neuron. Current noise enters the membrane equation directly while conductance noise is propagated through the activation variables. Compared with common used interspike interval method, ISI-distance is a simple complementary approach to measure the different effects of current and conductance noises. ISI-distance extracts information from the interspike intervals by evaluating the ratio of instantaneous firing rates, which is parameter-free, time scale-independent and easy to visualize. Simulation results show that the most significant differences between different noise implementations in a pacemaker-like tonic firing regime at the transition to chaotic burst discharges.