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Ki-67检测结果与乳腺癌临床病理指标的相关性分析 被引量：10

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摘要 Ki-67已成为预测乳腺癌患者治疗反应以及预后的重要生物学标志物。其检测一般采用免疫组织化学方法，但是目前尚无统一的操作指南对乳腺癌Ki-67免疫组织化学检测进行规范。我们采用组织芯片和计算机图像分析技术分析、评价各因素对Ki-67染色结果的影响，建立了乳腺癌Ki-67标准化免疫组织化学检测流程，并通过与乳腺癌分子分型等临床病理参数的相关性分析进一步验证其临床应用的有效性，为乳腺癌Ki-67规范化检测提供依据。
作者 邬万新 张怡 郭志琴 温晓伟 陆宁 袁琳娜 王振 唐正英 张燕萍
机构地区 浙江省嘉兴学院附属第一医院病理科
出处 《中华病理学杂志》 CAS CSCD 北大核心 2015年第9期657-658,共2页 Chinese Journal of Pathology
基金 浙江省省市共建医学扶植重点建设计划（GJJX-010-001） 嘉兴市科技计划项目（2012AY1070-9）
关键词 KI-67 乳腺癌患者 相关性分析 检测结果 临床病理指标 免疫组织化学方法 计算机图像分析技术 免疫组织化学检测
分类号 R737.9 [医药卫生—肿瘤]
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参考文献9

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共引文献6

同被引文献100

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二级引证文献45

中华病理学杂志
2015年 第9期

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