臭氧联合射频消融治疗极外侧型腰椎间盘突出症的疗效观察

Ozone injection combined with radiofrequency ablation for the treatment of far lateral lumbar disc herniation: observation of the curative effect

目的观察并探讨臭氧联合射频消融(RFA)治疗极外侧型腰椎间盘突出症(FLLDH)的临床疗效。方法对2013年3月—2014年3月收治的60例FLLDH患者按随机化原则分为对照组和研究组,对照组30例患者单行注射臭氧治疗,研究组30例患者行臭氧联合RFA,两组患者其他辅助无差别,每组患者治疗后随访1周和1、3、6个月,观察两组患者的临床疗效及有无并发症。结果 60例患者手术均获得成功,围手术期无并发症发生,技术成功率100%,对照组30例患者治疗后1周,1、3和6个月优良率分别为73.3%、76.7%、70.0%、60.0%,研究组分别为70.0%、76.7%、83.3%、90.0%。3、6个月时疗效显著优于对照组。结论臭氧联合RFA治疗极外侧型腰椎间盘突出是一种安全、有效的方法,值得临床推广应用。

Objective To investigate the clinical efficacy of ozone injection combined with radiofrequency ablation （RFA） for the treatment of far lateral lumbar disc herniation （FLLDH）. Methods A total of 60 patients with FLLDH, who were admitted to authors＇ hospital during the period from March 2013 to March 2014, were randomly and equally divided into the study group （n=30） and the control group （n=30）. Simple ozone injection treatment was employed for the patients of the control group, while ozone injection combined with radiofrequency ablation was adopted for the patients of the study group. The same other adjunctive medication was used in both groups. All the patients were followed up at one week as well as at one, 3 and 6 months after the treatment. The clinical effect and the complications of both groups were recorded. Results Successful operation was obtained in all 60 patients, no perioperative complications occurred, and the technical success rate was 100%. The excellent clinical results evaluated at one week, and one, 3 and 6 months after the treatment in the control group and in the study group were 73.3%, 76.7%, 70%, 60% and 70%, 76.7%, 83.3%, 90% respectively. The 3-month and 6-month clinical results of the study group were significantly better than those of the control group. Conclusion For the treatment of FLLDH, ozone injection combined with radiofrequency ablation is safe and effective. This technique should be recommended in clinical practice. （J Intervent Radiol, 2015, 24： 789-791）