胃肠道手术患者内源性感染分析与预防研究

Prevalence of endogenous infections in gastrointestinal surgery patients and prevention measures

目的探讨胃肠道手术患者内源性感染发生情况及预防措施,以有效降低患者感染率。方法回顾性分析2012年5月-2014年5月医院收治的200例接受胃肠道手术患者临床资料,采用SPSS 21.0统计软件对数据进行统计分析。结果 200例患者中12例发生了内源性感染,感染率6.00%;男女患者内源性感染率之间的差异无统计学意义;肿瘤、外伤、肠梗阻、其他患者的内源性感染率分别为1.2%、57.1%、16.7%、0,外伤患者的内源性感染率均明显高于肠梗阻和肿瘤患者(P<0.05);各类患者内源性感染率间的差异均无统计学意义;12例发生内源性感染患者共分离出12株病原菌,其中革兰阴性菌8株占66.7%,革兰阳性菌3株占25.0%;真菌1株占8.3%。结论胃肠道手术患者内源性感染发生的主要原因为外伤,主要病原菌为革兰阴性菌,临床应采取有针对性的措施进行预防。

OBJECTIVE To explore the prevalence of endogenous infections in the patients undergoing gastrointestinal surgery and put forward the prevention measures so as to effectively reduce the infection rate.METHODS The clinical data of 200 patients who underwent the gastrointestinal surgery in the hospital from May 2012 to May 2014 were retrospectively analyzed,and the statistical analysis of data was performed with the use of SPSS21.0software.RESULTS The endogenous infections occurred in 12 of 200patients,with the infection rate of 6.00%;there was no significant difference in the incidence of endogenous infections between the male patients and the female patients.The incidence of endogenous infections was 1.2%in the tumor patients,57.1%in the patients with trauma,16.7%in the patients with intestinal obstruction,and 0in other patients;the incidence of endogenous infections was significantly higher in the patients with trauma than in the tumor patients and the patients with intestinal obstruction（P〈0.05）.There was no significant difference in the incidence of endogenous infections among the patients with various kinds of diseases.A total of 12 strains of pathogens were isolated from the 12 patients with endogenous infections,including 8（66.7%）strains of gram-negative bacteria,3（25.0%）strains of gram-positive bacteria,and 1（8.3%）strain of fungus.CONCLUSIONThe trauma is the leading cause of the endogenous infections in the patients undergoing gastrointestinal surgery.The gram-negative bacteria are dominant among the pathogens.It is necessary for the hospital to take targeted prevention measures.