妊娠妇女下生殖道感染因素与病原菌分析

Influencing factors for lower genital tract infections in pregnant women and distribution of pathogens

目的探讨妊娠妇女下生殖道感染的失衡与感染因素的关系,为临床医护人员提供借鉴和参考。方法选取2013年1月-2015年1月于医院进行产前体检的妊娠妇女200例,其中早孕期妊娠妇女71例、中孕期妇女69例、晚孕期妇女60例,取其阴道或宫颈分泌物进行pH值、H2O2、病毒、衣原体属、细菌、真菌的培养,对多样性、菌群密集度、优势菌进行检测分析;使用SPSS20.0软件进行数据处理。结果 200例妊娠妇女中,77例发生下生殖道感染,感染率达38.5%;病原菌检测中检出病原菌失衡43例,占21.0%;职业、人流史、泌尿道感染、个人卫生习惯是下生殖道感染的影响因素(P<0.05)。结论妊娠期妇女病原菌失衡状态比重较大,增加其阴道感染率,对自身生活和下一代造成困扰,妊娠妇女应重视生殖道的常规检查和治疗。

OBJECTIVE To observe the relationship between the imbalance of lower genital tract infections in the pregnant women and the influencing factors so as to provide guidance for the health care workers.METHODS A total of 200 pregnant women who underwent the prenatal examination in the hospital from Jan 2013 to Jan 2015 were enrolled in the study,including 71 cases in first trimester,69 cases in second trimester,and 60 cases in third trimester.The vaginal or cervical secretions specimens were collected for the test of pH value and H2O2 and the culture of viruses,Chlamydia,bacteria,and fungi.The diversity,intensity of flora,and dominant bacteria were detected and analyzed.The statistical analysis of data was performed with the use of SPSS20.0software.RESULTS Of the 200 pregnant women,the lower genital tract infections occurred in 77 cases,with the infection rate of 38.5%.Totally 43 cases were detected positive for imbalance of pathogens,accounting for 21.0%.The influencing factors for the lower genital tract infections included the occupation,history of abortion,urinary tract infection,and personal hygiene habit（P〈0.05）.CONCLUSIONThe proportion of imbalance of pathogens is high among the pregnant women,which may increase the incidence of vaginal infections and trouble their lives as well as the next generation′s.Therefore,the pregnant women should pay great attention to the routine genital tract examination and treatment.