摘要
目的探讨实时三维超声心动图(RT-3DE)评价冠状动脉狭窄患者左心室收缩功能与同步性的临床应用价值。方法收集经冠状动脉造影证实左前降支(LAD)狭窄的患者50例,按狭窄程度分成Ⅰ组21例,狭窄率50%~75%;Ⅱ组29例,狭窄率≥76%。另选正常对照组60例,LAD无狭窄。所有患者均接受RT-3DE检查,通过脱机分析左心室17节段的容积-时间曲线,获取左心室整体收缩同步性参数(Tmsv-16-SD、Tmsv-16-SD%、Tmsv-16-Dif、Tmsv-16-Dif%)、LAD供血节段收缩功能参数(rEDV、rESV、rEF)及节段同步性参数(Tmsv%)。结果对照组节段射血分数(rEF)自基底段至心尖段逐渐增大,自基底段至中间段的差异有统计学意义(P〈0.05),而自中间段至心尖段差异无统计学意义(P〉0.05),Ⅰ组、Ⅱ组上述演变规律消失。Ⅱ组患者rEDV、rESV均明显增大,Tmsv-16-SD、Tmsv-16-SD%、Tmsv-16-Dif、Tmsv-16-Dif%、Tmsv%均明显延长,rEF明显降低(P均〈0.05),Ⅰ组患者上述各参数与对照组比较差异无统计学意义(P均〉0.05)。结论 RT-3DE可早期定量评价LAD不同程度狭窄患者左心室节段性收缩功能及收缩同步性的变化。
Objective To evaluate left ventricular systolic function and synchrony in patients with coronary artery stenosis by real-time three-dimensional echocardiography(RT-3DE).Methods Fifty patients with different degrees of left anterior descending(LAD)stenosis were divided into 2groups according to angiocardiography:GroupⅠincluding 21 patients with50%—75% LAD coronary artery stenosis,groupⅡincluding 29 patients with≥76% LAD coronary artery stenosis.Sixty subjects were in control group with no coronary stenosis.All patients were measured by RT-3DE.The 17-segmental volume-time curves of left ventricular were plotted,the global synchrony parameters(Tmsv-16-SD,Tmsv-16-SD%,Tmsv-16-Dif,Tmsv-16-Dif%)were obtained,meanwhile the regional systolic function parameters(rEDV,rESV,rEF)and synchrony parameter(Tmsv%)were required.Results The rEF of every segment in control group increased in a smooth progression from base to apex,there was significant statistical difference from base to middle(P〈0.05),but there was no statistical difference from middle to apex(P〉0.05);the rEF of every segment in group Ⅰ and group Ⅱlost the above regulation.rEDV and rESV increased significantly,rEF decreased obviously,Tmsv-16-SD,Tmsv-16-SD%,Tmsv-16-Dif,Tmsv-16-Dif% and Tmsv% were delayed significantly(all P〉0.05)in groupⅡ.The parameters between group I and control group had no significant differences(all P〉0.05).Conclusion RT-3DE can early quantitatively assess the changes of left ventricular regional systolic function and systolic synchrony in patients with different degree stenosis of LAD.
出处
《中国医学影像技术》
CSCD
北大核心
2015年第9期1326-1330,共5页
Chinese Journal of Medical Imaging Technology
关键词
超声心动描记术
三维
冠状动脉狭窄
心室功能
左
同步性
Echocardiolography
three-dimensional
Coronary artery stenosis
Ventricular function
left
Synchrony