胎儿超声心动图诊断单纯性室间隔缺损

Fetal echocardiography in diagnosis of isolated ventricular septal defect

目的探讨胎儿超声心动图检查对胎儿单纯性室间隔缺损的诊断价值。方法追踪随访我院建卡生产的37 253名孕妇,采用不同切面和手段检查胎儿单纯性室间隔缺损,并进行统计学分析。结果我院胎儿超声心动图检查对单纯性室间隔缺损诊断敏感度为73.44%(94/128),特异度为99.87%(37 076/37 125),阳性预测值为65.73%(94/143),阴性预测值为99.91%(37 076/37 110);不同检查切面的诊断效能两两比较差异均有统计学意义(P均<0.05);二维超声显示回声中断/失落与彩色多普勒超声显示心室水平分流比较,差异无统计学意义(P>0.05)。结论胎儿超声心动图检查诊断单纯性室间隔缺损具有较高敏感度,不同检查切面对该病诊断的意义不同。

Objective To explore the diagnostic value of fetal echocardiography in isolated ventricular septal defect.Methods Totally 37 253 pregnant women underwent regular prenatal examination and born in our hospital were followedup;isolated ventricular septal defect were examinated with different views and methods,and the statistical analysis was performed.Results The sensitivity,specificity,positive predictive value and negative predictive value of fetal echocardiography in diagnosis of simple isolated ventricular septal defect were 73.44%（94/128）,99.87%（37 076/37 125）,65.73%（94/143）,99.91%（37 076/37 110）,respectively;the different echocardiographic views of pairwise comparison had statistical difference（all P〉0.05）,and 2Decho interrupt/loss compared with color Doppler imaging of ventricular shunt had no statistical difference（P0.05）.Conclusion Fetal echocardiography in diagnosis of isolated ventricular septal defect has relatively high sensitivity,and different evaluation views in diagnosis of isolated ventricular septal defect has different significance.