新余市渝水区154例帕金森病危险因素调查研究

Investigation of the Risk Factors Associated with Parkinson's Disease in 154 Cases of Yushui District Xinyu City

目的:研究新余市渝水区门诊帕金森病相关危险因素。方法:病例组为2013年1月-2014年12月新余市渝水区来本院帕金森病专病门诊就诊的154例PD患者。对照组为同期新余市渝水区来本院神经内科就诊的154例其他患者。按照1∶1进行统计研究。结果:大专以上教育程度与PD的发生有显著性的联系(OR=0.23,95%CI=0.11-0.60),受教育程度越高是PD的危险因素。研究结果表明有家族史是PD的危险因素(OR=0.31,95%CI=0.15-0.68)。研究结果未发现与PD的发生有关,病例组和对照组之间的分布无显著性差别。结论:本文研究虽然排除了吸烟和饮酒对帕金森的影响,但不排除吸烟和饮酒对心脑血管疾病和神经系统疾病的危险因素影响。

Objective：To research the related risk factors of Parkinson’s disease in clinic Yushui District of Xinyu city.Method：154 PD patients from Xinyu Yushui district admitted to Parkinson’s disease special clinic of our hospital from January 2013 to December 2014 were selected as the case group.The 154 other patients for the same period in Xinyu City Yushui district to visit our hospital department of internal medicine were selected as the control group.The two groups were researched statistically according to 1∶1.Result：College degree or above education level had significant relationship with the incidence of PD（OR=0.23,95%CI=0.11-0.60）,the higher education level was the risk factor of PD.The results showed that the family history was a risk factor for PD（OR=0.31,95%CI=0.15-0.68）.There was no significant difference in the distribution between the case group and the control group.The results were not found to have a significant difference between the patients and the control group.Conclusion：This study excludes the effect of smoking and alcohol drinking on Parkinson,but don’t rule out the risk factors of smoking and alcohol drinking on cardiovascular and cerebrovascular diseases and neurological diseases.